{"id":"W2002561997","doi":"10.1371/journal.pone.0004953","title":"C5a Enhances Dysregulated Inflammatory and Angiogenic Responses to Malaria In Vitro: Potential Implications for Placental Malaria","year":2009,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Malaria Research and Control","field":"Medicine","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Toronto General Hospital; University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; U.S. Public Health Service; Canada Research Chairs; National Institutes of Health; Canadian Institutes of Health Research; Genome Canada; Ontario Genomics; Ontario Genomics Institute","keywords":"Malaria; In vitro; Inflammation; Immunology; Biology; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003599094,0.0002499626,0.0001951204,0.0002346266,0.0002128758,0.0002828117,0.0001733738,0.0002211046,0.00146735],"category_scores_gemma":[0.0003508897,0.00009984393,0.0001248889,0.0001977323,0.0002706368,0.0001086092,0.0002206648,0.0003251843,0.0001647026],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004001611,"about_ca_system_score_gemma":0.0003328095,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002012665,"about_ca_topic_score_gemma":0.002159549,"domain_scores_codex":[0.9998307,0.00007176355,0.00001257953,0.00001369382,0.00002296969,0.00004809516],"domain_scores_gemma":[0.9998784,0.00004373267,0.00002636418,0.00001318998,0.00001451914,0.00002382305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003087737,0.0002450779,0.004129212,0.000355805,0.00002594872,0.0004322029,0.0001372952,0.0001349272,0.984427,0.0001964876,0.0002318089,0.006596382],"study_design_scores_gemma":[0.0001933537,0.005218111,0.1277644,0.0001566665,0.0001035001,0.002072153,0.000402783,0.001966086,0.8547531,0.0001831247,0.007170076,0.00001655495],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930249,0.004785113,0.0006510493,0.0001672668,0.00001953434,0.00006266238,0.0002421734,0.00001410756,0.00103305],"genre_scores_gemma":[0.9968773,0.001694934,0.0007142159,0.00006437599,0.00001384203,0.0000468997,0.0001942862,0.000002127198,0.0003920669],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002012665,"threshold_uncertainty_score":0.004908741,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02149530304488452,"score_gpt":0.2715354117699454,"score_spread":0.2500401087250609,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}