{"id":"W2002630715","doi":"10.1371/journal.pone.0038175","title":"Colorectal Cancer Linkage on Chromosomes 4q21, 8q13, 12q24, and 15q22","year":2012,"lang":"zh","type":"article","venue":"PLoS ONE","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Memorial University of Newfoundland","funders":"National Institute of Environmental Health Sciences; National Cancer Institute; University of California, Irvine; Cancer Research UK","keywords":"Microsatellite instability; Genetic linkage; Genetics; Colorectal cancer; Single-nucleotide polymorphism; Medicine; Microsatellite; Family history; Cancer; Biology; Internal medicine; Genotype; Gene; Allele","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008940992,0.0004915576,0.000537314,0.002599044,0.000940256,0.0006315883,0.0005558716,0.0004015157,0.005390414],"category_scores_gemma":[0.00295333,0.0003598157,0.0005507016,0.001789657,0.0004069667,0.0001719343,0.0008878747,0.0003262612,0.0003454809],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001119773,"about_ca_system_score_gemma":0.0007634738,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03052409,"about_ca_topic_score_gemma":0.04896687,"domain_scores_codex":[0.9989384,0.0003081516,0.0000619328,0.0002887482,0.0001892732,0.0002135177],"domain_scores_gemma":[0.9988978,0.0002682981,0.0004635965,0.00007505781,0.0001104875,0.0001847411],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008006378,0.00007804514,0.9497095,0.0001014514,0.0005931205,0.001821433,0.0004418157,0.0008177248,0.01461031,0.000511643,0.0009589675,0.02955553],"study_design_scores_gemma":[0.00005298464,0.0001536477,0.9935702,0.0000393513,0.0001924789,0.001434776,0.00009744594,0.0004071404,0.001042986,0.0002826808,0.002715668,0.00001067051],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951579,0.001614291,0.0007983093,0.0001278054,0.000012934,0.00003811776,0.0008142114,0.00004475379,0.001391713],"genre_scores_gemma":[0.9949331,0.0006074365,0.001518947,0.00006164696,0.00001661872,0.00005650018,0.001063134,0.000007770578,0.001734966],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03052409,"threshold_uncertainty_score":0.06069285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05449570107164878,"score_gpt":0.2758359078810224,"score_spread":0.2213402068093736,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}