{"id":"W2002666280","doi":"10.1155/2013/290565","title":"Pharmacological Inhibition of p38 Mitogen-Activated Protein Kinases Affects KC/CXCL1-Induced Intraluminal Crawling, Transendothelial Migration, and Chemotaxis of Neutrophils<i>In Vivo</i>","year":2013,"lang":"en","type":"article","venue":"Mediators of Inflammation","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"Chemotaxis; p38 mitogen-activated protein kinases; Cell biology; CXCL1; Biology; MAPK/ERK pathway; Chemokine; In vivo; Intravital microscopy; Kinase; Downregulation and upregulation; Inflammation; Protein kinase A; Immunology; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001704282,0.0005304706,0.0003291894,0.0001817388,0.0001514055,0.0001884868,0.0002458284,0.0002276219,0.001262516],"category_scores_gemma":[0.00009130504,0.0001315724,0.0002928606,0.000120834,0.0002560377,0.0002398542,0.000131665,0.000677869,0.0002909886],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002576163,"about_ca_system_score_gemma":0.0002657398,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005481779,"about_ca_topic_score_gemma":0.0008894764,"domain_scores_codex":[0.999873,0.00001952764,0.0000146239,0.00002036148,0.00002036728,0.00005205549],"domain_scores_gemma":[0.9999385,0.000008714695,0.00001937852,0.000004991892,0.000006697949,0.00002165156],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004139264,0.0001373651,0.00007263345,0.00008654902,0.000004633579,0.00004113127,0.00001454756,0.00004059447,0.9979172,0.00006091064,0.00004771011,0.001162744],"study_design_scores_gemma":[0.00004568603,0.001341162,0.002748726,0.000008457515,0.00001905312,0.0001383452,0.00002615963,0.0007496267,0.9936584,0.00003431244,0.001225475,0.000004517847],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941679,0.002704433,0.001556209,0.0001553937,0.00005241859,0.00003823402,0.0002816074,0.00008426431,0.0009595917],"genre_scores_gemma":[0.9903691,0.003113619,0.003173693,0.00008353632,0.00003222757,0.0001396256,0.0005347087,0.00001936493,0.002534016],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001262516,"threshold_uncertainty_score":0.004223526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01221320441607795,"score_gpt":0.2635655193748839,"score_spread":0.2513523149588059,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}