{"id":"W2002681960","doi":"10.1080/01635580903532440","title":"The Effect of Secoisolariciresinol Diglucoside and Flaxseed Oil, Alone and in Combination, on MCF-7 Tumor Growth and Signaling Pathways","year":2010,"lang":"en","type":"article","venue":"Nutrition and Cancer","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Canadian Breast Cancer Research Alliance; Breast Cancer Alliance","keywords":"MCF-7; Endocrinology; Estrogen receptor; Internal medicine; Apoptosis; Cell growth; Chemistry; Estrogen; Ovariectomized rat; Receptor; Signal transduction; Biology; Pharmacology; Biochemistry; Cancer; Breast cancer; Medicine; Human breast","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001087144,0.000498366,0.0005205096,0.000362004,0.000154967,0.0002418781,0.0002126538,0.0003387945,0.001067108],"category_scores_gemma":[0.0001516041,0.0001466297,0.0002722942,0.0002195879,0.0001978747,0.0002226071,0.0001694162,0.000502353,0.0001799436],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002806133,"about_ca_system_score_gemma":0.000362691,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001469507,"about_ca_topic_score_gemma":0.004140109,"domain_scores_codex":[0.9998769,0.00003243351,0.00001034885,0.00001843043,0.00002041795,0.00004145593],"domain_scores_gemma":[0.9998434,0.0000346115,0.0000263789,0.0000108056,0.00001191466,0.0000729672],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.009894322,0.001138639,0.0006896676,0.0001521106,0.0000848894,0.0001170334,0.00005567278,0.0003465326,0.9774888,0.00007607514,0.0002246761,0.009731616],"study_design_scores_gemma":[0.0007258141,0.0272349,0.01619408,0.00002456601,0.0003156299,0.0002944447,0.0001818929,0.001784612,0.94805,0.00008494164,0.005079356,0.000029743],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964904,0.001698503,0.0002253471,0.0001092098,0.00005124671,0.00003085029,0.0001905156,0.00003878237,0.001165067],"genre_scores_gemma":[0.9956371,0.001294466,0.000652912,0.00007563665,0.00002767686,0.00003423302,0.0002562432,0.000007663818,0.002014045],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001469507,"threshold_uncertainty_score":0.003569841,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003034134620598753,"score_gpt":0.2127679891564105,"score_spread":0.2097338545358117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}