{"id":"W2002763682","doi":"10.1074/jbc.m111.234336","title":"Fetal Cardiac Troponin Isoforms Rescue the Increased Ca2+ Sensitivity Produced by a Novel Double Deletion in Cardiac Troponin T Linked to Restrictive Cardiomyopathy","year":2011,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cardiomyopathy and Myosin Studies","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Heart Institute; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Heart, Lung, and Blood Institute; Deutsche Herzstiftung; American Heart Association","keywords":"Cardiology; Internal medicine; Troponin; Fetus; Medicine; Troponin T; Cardiomyopathy; Gene isoform; Heart failure; Chemistry; Pregnancy; Biology; Biochemistry; Myocardial infarction; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009908193,0.000544055,0.0002360172,0.0001696057,0.0001136885,0.000163016,0.0002885897,0.0003829689,0.00109286],"category_scores_gemma":[0.0002217288,0.0001427435,0.0001855614,0.00009237761,0.0002463726,0.00008045482,0.0002654362,0.0003942835,0.000309248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001244076,"about_ca_system_score_gemma":0.0001426764,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004346751,"about_ca_topic_score_gemma":0.0005080287,"domain_scores_codex":[0.9999171,0.00001206923,0.00001187441,0.00002429089,0.00002173923,0.00001284501],"domain_scores_gemma":[0.9998547,0.00003048988,0.00003805301,0.00001683388,0.000008714712,0.00005126627],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007588622,0.00001673278,0.00040975,0.00001340109,0.000004097959,0.00132312,0.00001676768,0.00009582831,0.9968353,0.00003578081,0.00002175,0.001151685],"study_design_scores_gemma":[0.0001701394,0.0008164656,0.0335086,0.00002343291,0.00006627321,0.0337387,0.00008302976,0.003537779,0.9237888,0.0001750502,0.004066318,0.0000253589],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979091,0.000161254,0.001326493,0.00002969877,0.00001109212,0.00001009084,0.000112611,0.00004610406,0.0003935836],"genre_scores_gemma":[0.9969823,0.0001783435,0.001594949,0.00002658153,0.000006119755,0.00001371034,0.0002966266,0.00003954941,0.0008618658],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00109286,"threshold_uncertainty_score":0.00365597,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03303090402183888,"score_gpt":0.2571202370506342,"score_spread":0.2240893330287954,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}