{"id":"W2002784664","doi":"10.1021/om060733d","title":"Synthesis and Characterization of Gold(I) <i>N</i>-Heterocyclic Carbene Complexes Bearing Biologically Compatible Moieties","year":2006,"lang":"en","type":"article","venue":"Organometallics","topic":"Synthetic Organic Chemistry Methods","field":"Chemistry","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Eli Lilly and Company","keywords":"Chemistry; Auranofin; Carbene; Ligand (biochemistry); Yield (engineering); Nuclear magnetic resonance spectroscopy; Medicinal chemistry; Ferrocene; Thio-; Combinatorial chemistry; Stereochemistry; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001579894,0.000249949,0.0004866483,0.00005771246,0.0000661351,0.00004623577,0.0002503851,0.0001771926,0.001727139],"category_scores_gemma":[0.0001469985,0.0002381498,0.00007903904,0.0002040843,0.0002301139,0.00007863612,0.0001646684,0.000124546,0.000006398012],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004486589,"about_ca_system_score_gemma":0.0000165513,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007196327,"about_ca_topic_score_gemma":0.000005318741,"domain_scores_codex":[0.9986406,0.00003842563,0.0004898714,0.0003645091,0.0002024274,0.0002641608],"domain_scores_gemma":[0.9989119,0.0002899194,0.0002747711,0.0003900748,0.00006505644,0.00006830638],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001116891,0.00009255428,0.01056765,0.0002008396,0.0000391948,0.000001392665,0.00004785086,0.000002354813,0.9861907,0.0001930618,0.000004391004,0.002648887],"study_design_scores_gemma":[0.0001826575,0.00001050979,0.01899729,0.00005179299,0.00006882445,0.00001901554,0.00005778482,0.00009781557,0.9785014,0.0002355895,0.00153422,0.0002430868],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991577,0.0001383181,0.0003798459,0.00007715907,0.00003694199,0.00005610503,0.00009267867,0.0001114604,0.007530474],"genre_scores_gemma":[0.9950116,0.0001026638,0.003789555,0.00001503779,0.0001182446,0.00001231728,0.00009447488,0.0000424778,0.000813584],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008429648,"threshold_uncertainty_score":0.9991854,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01731153663834859,"score_gpt":0.2295636030727533,"score_spread":0.2122520664344047,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}