{"id":"W2002820097","doi":"10.1016/j.yexcr.2009.08.021","title":"fps/fes knockout mice display a lactation defect and the fps/fes tyrosine kinase is a component of E-cadherin-based adherens junctions in breast epithelial cells during lactation","year":2009,"lang":"en","type":"article","venue":"Experimental Cell Research","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"National Cancer Institute; Canadian Cancer Society","keywords":"Adherens junction; Biology; Cell biology; Lactation; Knockout mouse; Tyrosine kinase; Conditional gene knockout; Myoepithelial cell; Cancer research; Internal medicine; Cadherin; Endocrinology; Signal transduction; Immunology; Cell; Phenotype; Receptor; Medicine; Gene; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002504056,0.001002246,0.0003816565,0.00111261,0.0004559293,0.000444424,0.0004850548,0.001149234,0.004715788],"category_scores_gemma":[0.0002568053,0.0006379,0.0003903077,0.0002496497,0.00120869,0.0005675926,0.0003810047,0.00154972,0.0008897743],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004552302,"about_ca_system_score_gemma":0.0002922408,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009288423,"about_ca_topic_score_gemma":0.001546096,"domain_scores_codex":[0.9997391,0.00003007417,0.00003091375,0.0000655466,0.00007287363,0.00006155689],"domain_scores_gemma":[0.9993514,0.00008440973,0.0002901038,0.0000325395,0.0000248021,0.0002167862],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003456919,0.00002430376,0.0002421271,0.00001987213,0.000006028283,0.0002815329,0.00003062565,0.00004563156,0.9978969,0.0002636983,0.00008517582,0.0007583754],"study_design_scores_gemma":[0.00009581601,0.0002119259,0.01538382,0.00002364151,0.00004247623,0.003684358,0.0001788024,0.0009254161,0.9743561,0.000454752,0.00461931,0.0000235326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909779,0.001081233,0.003611044,0.0005097763,0.00006916331,0.00001886564,0.002087057,0.0002716557,0.001373452],"genre_scores_gemma":[0.9761038,0.0009742362,0.003160939,0.0001500656,0.00003986667,0.00006458534,0.001880624,0.0002155824,0.01741026],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004715788,"threshold_uncertainty_score":0.01577592,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01687824031884253,"score_gpt":0.3045795264025222,"score_spread":0.2877012860836796,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}