{"id":"W2002820097","doi":"10.1016/j.yexcr.2009.08.021","title":"fps/fes knockout mice display a lactation defect and the fps/fes tyrosine kinase is a component of E-cadherin-based adherens junctions in breast epithelial cells during lactation","year":2009,"lang":"en","type":"article","venue":"Experimental Cell Research","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"National Cancer Institute; Canadian Cancer Society","keywords":"Adherens junction; Biology; Cell biology; Lactation; Knockout mouse; Tyrosine kinase; Conditional gene knockout; Myoepithelial cell; Cancer research; Internal medicine; Cadherin; Endocrinology; Signal transduction; Immunology; Cell; Phenotype; Receptor; Medicine; Gene; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004097605,0.000156487,0.0001586258,0.0001100771,0.0001855875,0.00004183239,0.0001509403,0.00009428236,0.00007914147],"category_scores_gemma":[0.00001329851,0.0001261114,0.00008423343,0.0001922661,0.0002739257,0.00001090752,0.00007130138,0.0001676457,0.000009841428],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007117745,"about_ca_system_score_gemma":0.00008946354,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002292251,"about_ca_topic_score_gemma":0.00002899451,"domain_scores_codex":[0.9985568,0.000228401,0.0002551897,0.000330778,0.0003342122,0.0002946194],"domain_scores_gemma":[0.9995213,0.00005937494,0.00007640738,0.0001703977,0.00010513,0.00006735525],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001570143,0.0002575399,0.0007426837,0.00003361497,0.00001735839,0.00000285995,0.00117424,0.00004571598,0.9954897,0.00001499809,0.0003282831,0.0003229101],"study_design_scores_gemma":[0.002995424,0.0002567976,0.01001248,0.00004547093,0.000007997018,0.000003819819,0.00103847,0.0002230249,0.9849772,0.00001693296,0.0002808026,0.0001415851],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969586,0.001779253,0.00002530598,0.0002506776,0.0000789143,0.0004206347,0.00002900133,0.000007511918,0.0004500786],"genre_scores_gemma":[0.9986664,0.0001428968,0.0001808388,0.00006298575,0.00008249991,0.00008591977,0.00007762136,0.00001718615,0.000683647],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01051246,"threshold_uncertainty_score":0.5142672,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01687824031884253,"score_gpt":0.3045795264025222,"score_spread":0.2877012860836796,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}