{"id":"W2002851531","doi":"10.1081/ncn-200065964","title":"SYNTHESIS AND PROPERTIES OF PNA OLIGOMERS CONTAINING OROTIC ACID DERIVATIVES","year":2005,"lang":"en","type":"article","venue":"Nucleosides Nucleotides & Nucleic Acids","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Peptide nucleic acid; Uracil; Chemistry; Nucleobase; Monomer; Thymine; Chemical modification; Orotic acid; Nucleic acid; Residue (chemistry); Oligomer; Polymer chemistry; Combinatorial chemistry; Organic chemistry; DNA; Polymer; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003091363,0.0005128815,0.0005922201,0.0001131383,0.0002442409,0.00008849959,0.0005308515,0.0003129167,0.0001605992],"category_scores_gemma":[0.0005078879,0.0004815457,0.0002136946,0.0001845185,0.0009012939,0.00006145196,0.0004074354,0.0002221886,0.00003447212],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004468009,"about_ca_system_score_gemma":0.00007790669,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002457217,"about_ca_topic_score_gemma":0.00001469403,"domain_scores_codex":[0.9975277,0.00009271938,0.0006702251,0.0007543889,0.0003286223,0.0006263886],"domain_scores_gemma":[0.9985051,0.00004586372,0.0003078153,0.0006954731,0.000184972,0.0002607646],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003156801,0.0001226238,0.006118653,0.0001596873,0.0002112124,0.000004326259,0.0005944345,0.00002171503,0.9694331,0.000204457,0.0005084288,0.02230567],"study_design_scores_gemma":[0.000710074,0.0002988589,0.004145104,0.0002248373,0.0001092759,0.00006603384,0.001595374,0.0002147543,0.9796765,0.00004970781,0.01232679,0.0005827081],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924194,0.002438686,0.00006554393,0.0005090316,0.00008826744,0.0002597615,0.00002365731,0.00009486312,0.004100827],"genre_scores_gemma":[0.9935227,0.0005832661,0.004666757,0.0005187683,0.000309256,0.00003723749,0.00001191029,0.0001316748,0.0002184334],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02172296,"threshold_uncertainty_score":0.9997636,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01135334655177417,"score_gpt":0.2192558600451343,"score_spread":0.2079025134933601,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}