{"id":"W2002882735","doi":"10.1074/jbc.m302780200","title":"Inhibition of Plasminogen Activation by Lipoprotein(a)","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":149,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Heart and Stroke Foundation of Canada","keywords":"Kringle domain; Plasmin; Chemistry; Lipoprotein(a); Urokinase; Plasminogen activator; Biochemistry; Protease; Cofactor; Apolipoprotein B; Ternary complex; Fibrinolysis; Fibrin; Recombinant DNA; Binding site; Tissue plasminogen activator; Molecular biology; Enzyme; Biology; Cholesterol; Immunology; Internal medicine; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001954912,0.0003041124,0.0002126808,0.0001144276,0.00009820882,0.0003293529,0.0002357948,0.0002267896,0.0006951745],"category_scores_gemma":[0.0002790377,0.0001224657,0.0002419328,0.0001143867,0.0001688489,0.0001093544,0.0001407941,0.0003531789,0.0002838818],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003952205,"about_ca_system_score_gemma":0.0002419586,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008206287,"about_ca_topic_score_gemma":0.0004613854,"domain_scores_codex":[0.9997721,0.00004959549,0.0000180342,0.00004822604,0.00005701202,0.00005508947],"domain_scores_gemma":[0.9998388,0.00005826048,0.00004013861,0.00002361815,0.00002037387,0.00001868553],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001256121,0.00004033359,0.0001142015,0.0000235413,0.000005942571,0.00001534895,0.000008265509,0.00009896175,0.997153,0.00007466748,0.0000314258,0.002308578],"study_design_scores_gemma":[0.00001198034,0.0002671951,0.0009850881,0.000002470642,0.000004744376,0.00008766745,0.000002985032,0.001142172,0.9968304,0.00002109351,0.0006412796,0.000002974146],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937505,0.001657165,0.003257982,0.00003338935,0.00001367757,0.00002197004,0.000087974,0.00007540893,0.001101967],"genre_scores_gemma":[0.995404,0.0004918599,0.002498041,0.00002158871,0.000004543072,0.00001899102,0.0001855588,0.00000911625,0.001366317],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008206287,"threshold_uncertainty_score":0.002867579,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01325246799640966,"score_gpt":0.2276603895879102,"score_spread":0.2144079215915005,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}