{"id":"W2002905271","doi":"10.1016/j.bbadis.2006.03.001","title":"Innate immunity in amyotrophic lateral sclerosis","year":2006,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":143,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"National Science Council","keywords":"Amyotrophic lateral sclerosis; Innate immune system; Neuroinflammation; Neuroscience; Excitotoxicity; Motor neuron; Neurodegeneration; Microglia; Biology; Inflammation; Immunity; Immunology; Disease; Medicine; Immune system; Glutamate receptor; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007595385,0.0009794203,0.002176079,0.001708589,0.0003020375,0.001084842,0.001032822,0.001264924,0.002165907],"category_scores_gemma":[0.0004726958,0.0002995327,0.0003971071,0.001752727,0.0006218229,0.001492902,0.0007112934,0.001895905,0.002024428],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005943929,"about_ca_system_score_gemma":0.001014723,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007622314,"about_ca_topic_score_gemma":0.001516378,"domain_scores_codex":[0.9998521,0.00002553039,0.00002783376,0.00002202659,0.00005603769,0.00001638975],"domain_scores_gemma":[0.9997807,0.00008212675,0.00003889188,0.000006481182,0.00006165604,0.00003023647],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003232245,0.0001158321,0.0002943759,0.01468386,0.0001202718,0.0005196249,0.00007504985,0.0004327751,0.003995138,0.00353272,0.03120657,0.9447006],"study_design_scores_gemma":[0.00009982811,0.0001436722,0.001152115,0.003233504,0.0001917192,0.002182928,0.00009374138,0.0001020228,0.0007413556,0.002736914,0.9892967,0.00002553087],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008561944,0.9990892,0.00008462872,0.0001451754,0.0002224759,0.000003025839,0.000007830367,0.000003692755,0.0003583031],"genre_scores_gemma":[0.0006583264,0.9983095,0.0001826326,0.0001489099,0.000247206,0.000005786784,0.00001989411,5.399622e-7,0.0004270927],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002176079,"threshold_uncertainty_score":0.007245719,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04592679394257043,"score_gpt":0.3328269474847906,"score_spread":0.2869001535422201,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}