{"id":"W2002929600","doi":"10.1182/blood-2002-01-0235","title":"Donor-lymphocyte infusion induces transplantation tolerance by activating systemic and graft-infiltrating double-negative regulatory T cells","year":2002,"lang":"en","type":"article","venue":"Blood","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":93,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"","keywords":"Transplantation; CD8; Immunology; Immune tolerance; Cytotoxic T cell; T cell; Mixed lymphocyte reaction; Medicine; Immune system; Biology; In vitro; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002884722,0.0007161989,0.0003646118,0.0003060408,0.0001310023,0.0003335578,0.0002068248,0.0002632868,0.001490184],"category_scores_gemma":[0.000169198,0.0001388133,0.0001571738,0.0001386466,0.0003502794,0.0001692874,0.0001633072,0.000963799,0.0004574903],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002619774,"about_ca_system_score_gemma":0.0002054421,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001050955,"about_ca_topic_score_gemma":0.0001885841,"domain_scores_codex":[0.9997068,0.00006475764,0.00002060184,0.00007302057,0.00004845218,0.00008628355],"domain_scores_gemma":[0.9998525,0.00003160399,0.00004818729,0.000018569,0.000007534728,0.0000415547],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009862637,0.0004590298,0.0007804772,0.00009889476,0.00001030598,0.0002002507,0.00003356043,0.0001089027,0.9850256,0.0002906831,0.0001471835,0.01185883],"study_design_scores_gemma":[0.0004010669,0.00682382,0.006285222,0.00003147183,0.00007232549,0.002099874,0.00003968484,0.001745434,0.9768866,0.0002039697,0.005401165,0.000009424843],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915879,0.00154167,0.003053172,0.00006346397,0.00005388383,0.00006122111,0.0001046938,0.0003290934,0.003204819],"genre_scores_gemma":[0.9943227,0.0006329929,0.002418103,0.00007942762,0.00004648138,0.00005828709,0.0002515033,0.00004389841,0.002146713],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001490184,"threshold_uncertainty_score":0.004985154,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01109552012531124,"score_gpt":0.1976628801008054,"score_spread":0.1865673599754942,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}