{"id":"W2002929600","doi":"10.1182/blood-2002-01-0235","title":"Donor-lymphocyte infusion induces transplantation tolerance by activating systemic and graft-infiltrating double-negative regulatory T cells","year":2002,"lang":"en","type":"article","venue":"Blood","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":93,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"","keywords":"Transplantation; CD8; Immunology; Immune tolerance; Cytotoxic T cell; T cell; Mixed lymphocyte reaction; Medicine; Immune system; Biology; In vitro; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001543633,0.0002684184,0.0003415382,0.00009184677,0.000408126,0.00003267693,0.0001648159,0.000383864,0.0001498809],"category_scores_gemma":[0.00001219831,0.0002480719,0.0000563104,0.0001472356,0.000203267,0.0002258341,0.00003986487,0.0003409832,0.0001061641],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003193905,"about_ca_system_score_gemma":0.00002264319,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002117783,"about_ca_topic_score_gemma":0.00001477862,"domain_scores_codex":[0.998518,0.0001941161,0.0004156764,0.0004284333,0.00004948637,0.000394231],"domain_scores_gemma":[0.9992272,0.0002095762,0.0002676916,0.0002169661,0.00005052062,0.00002808679],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001061856,0.000176457,0.0005686674,0.00009164403,0.0001200338,0.000007945313,0.002968507,0.000005500424,0.99169,0.00004852457,0.0002083481,0.004008164],"study_design_scores_gemma":[0.007152779,0.0001711078,0.0003376177,0.0001930707,0.00008591539,0.0003796823,0.0005967077,0.00001190486,0.9900699,0.00001596055,0.0006946527,0.0002906887],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9876843,0.01005906,0.00003068303,0.00005175374,0.0003799913,0.0003162668,0.0000303736,0.0001233996,0.001324152],"genre_scores_gemma":[0.9970434,0.001418997,0.0001121308,0.00007967861,0.00004238567,0.00003813759,0.00005122911,0.00002345937,0.001190525],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009359137,"threshold_uncertainty_score":0.9999971,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01109552012531124,"score_gpt":0.1976628801008054,"score_spread":0.1865673599754942,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}