{"id":"W2003027167","doi":"10.1007/s13555-014-0043-4","title":"Health-Related Quality of Life Worsens Disproportionately to Objective Signs of Psoriasis After Withdrawal of Adalimumab Therapy","year":2014,"lang":"en","type":"article","venue":"Dermatology and Therapy","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre de Recherche Dermatologique du Québec Métropolitain","funders":"AbbVie","keywords":"Medicine; Discontinuation; Psoriasis; Dermatology Life Quality Index; Adalimumab; Psoriasis Area and Severity Index; Internal medicine; Quality of life (healthcare); Randomized controlled trial; Placebo; Severity of illness; Physical therapy; Disease; Dermatology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003018555,0.0003015866,0.001512975,0.0002641472,0.0002796158,0.0006158788,0.0002081507,0.0004022559,0.00212184],"category_scores_gemma":[0.00370892,0.0002093081,0.00100255,0.0003267322,0.0002965174,0.0003394823,0.0002864827,0.001026396,0.0002092309],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003547593,"about_ca_system_score_gemma":0.0004393223,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003363039,"about_ca_topic_score_gemma":0.0006114169,"domain_scores_codex":[0.9985776,0.0005806196,0.0001433685,0.0001775122,0.000303571,0.0002173915],"domain_scores_gemma":[0.9958461,0.001190641,0.00195324,0.0002993902,0.0002472115,0.0004635344],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.2376216,0.00350315,0.667154,0.000418335,0.002825845,0.0003100029,0.0002022378,0.000543155,0.02131558,0.00004851699,0.0007560042,0.06530153],"study_design_scores_gemma":[0.003202145,0.02461381,0.9693074,0.00002277075,0.0004745535,0.0004472387,0.00004005185,0.0002370719,0.001111734,0.00004329742,0.0004874152,0.00001249052],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984846,0.0008199499,0.00007250223,0.00004663211,0.000009712013,0.00004114014,0.0001113393,0.000004687196,0.0004095031],"genre_scores_gemma":[0.9993886,0.0001240543,0.00004486243,0.00006489261,0.00002133295,0.00002923227,0.0001513131,0.000001660137,0.0001740439],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003018555,"threshold_uncertainty_score":0.01596385,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02056653776895022,"score_gpt":0.2686766348476873,"score_spread":0.2481100970787371,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}