{"id":"W2003045129","doi":"10.1200/jco.2007.12.2481","title":"Absence of Secondary Malignant Neoplasms in Children With High-Risk Acute Lymphoblastic Leukemia Treated With Dexrazoxane","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Chemotherapy-induced cardiotoxicity and mitigation","field":"Medicine","cited_by":118,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine","funders":"National Cancer Institute; National Institutes of Health; Enzon Pharmaceuticals; American Society of Clinical Oncology; Pfizer","keywords":"Medicine; Lymphoblastic Leukemia; Dexrazoxane; Oncology; Internal medicine; Cancer research; Leukemia; Cancer; Anthracycline; Breast cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009123244,0.0001706749,0.001542266,0.0001734204,0.00003584413,0.000002866314,0.0001235361,0.0003623496,0.00005092145],"category_scores_gemma":[0.0003194578,0.0001051032,0.0002237997,0.0002857549,0.0004143508,0.0001200776,0.00001600091,0.0009036243,0.000004028689],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003008829,"about_ca_system_score_gemma":0.003449685,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002284458,"about_ca_topic_score_gemma":0.000122187,"domain_scores_codex":[0.9974535,0.0002323477,0.001509797,0.0002099632,0.0003734634,0.0002209069],"domain_scores_gemma":[0.9969168,0.0007225291,0.001615213,0.000199345,0.0002984979,0.0002476093],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01198579,0.0008493956,0.9443883,0.00001983255,0.001607538,0.00199166,0.000190312,0.0004049589,0.01042948,0.00001735643,0.00020535,0.02791],"study_design_scores_gemma":[0.02144449,0.01923889,0.9162647,0.0002535542,0.0005133309,0.01164228,0.00004691214,0.00004772736,0.0302601,0.00003933074,0.000130657,0.0001180686],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986334,0.000087183,0.0002495874,0.0002846074,0.00009633273,0.0002412601,0.000009675738,0.000009306125,0.0003886232],"genre_scores_gemma":[0.9944676,0.001332153,0.003283141,0.0005056254,0.0002850194,0.000002872506,0.00000710416,0.00002142889,0.00009502743],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02812367,"threshold_uncertainty_score":0.6119593,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02569838649803667,"score_gpt":0.3232095574555233,"score_spread":0.2975111709574866,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}