{"id":"W2003053754","doi":"10.1016/j.jchromb.2008.11.020","title":"Immunodepletion of high abundance proteins coupled on-line with reversed-phase liquid chromatography: A two-dimensional LC sample enrichment and fractionation technique for mammalian proteomics","year":2008,"lang":"en","type":"article","venue":"Journal of Chromatography B","topic":"Advanced Proteomics Techniques and Applications","field":"Chemistry","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dow Chemical (Canada)","funders":"","keywords":"Chemistry; Chromatography; Proteomics; Fractionation; Sample preparation; Proteome; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002982283,0.0002725902,0.0004621889,0.0003634103,0.0003071491,0.00001680327,0.0001930532,0.0001473032,0.00003760587],"category_scores_gemma":[0.00004669005,0.0002361894,0.0002192798,0.0004292948,0.0002354296,0.0002417006,0.00002954799,0.0003288618,2.055028e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000775485,"about_ca_system_score_gemma":0.0001463303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007187516,"about_ca_topic_score_gemma":0.00000363628,"domain_scores_codex":[0.9982236,0.00002046769,0.0007914401,0.0002836038,0.0004360998,0.0002447565],"domain_scores_gemma":[0.9974064,0.0001334336,0.001400264,0.0003239699,0.0006251815,0.0001107124],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002766456,0.0009039312,0.0004989614,0.0002182867,0.0001624527,0.00001004551,0.00005226508,0.0007348767,0.9919009,0.002517917,0.0001022637,0.0001316721],"study_design_scores_gemma":[0.004748058,0.00267668,0.0002520037,0.0005182902,0.00008240381,0.00061099,0.0000261779,0.0008276145,0.9855832,0.003497895,0.000858995,0.0003176995],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.641822,0.0001123409,0.3566768,0.0001787916,0.00001680544,0.001000072,0.000128748,0.00004201189,0.00002244742],"genre_scores_gemma":[0.6547228,0.0001405331,0.3443537,0.0000346412,0.00007919616,0.0005725002,0.0000565249,0.00003285291,0.000007290089],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01290074,"threshold_uncertainty_score":0.9631526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01373222477935198,"score_gpt":0.2799503792382631,"score_spread":0.2662181544589111,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}