{"id":"W2003058643","doi":"10.1158/1541-7786.mcr-07-0068","title":"Oncogenic Activation of the Human <i>Pygopus2</i> Promoter by E74-Like Factor-1","year":2008,"lang":"en","type":"article","venue":"Molecular Cancer Research","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Transcription factor; Chromatin immunoprecipitation; Biology; Wnt signaling pathway; Promoter; Gene silencing; Molecular biology; Transcription (linguistics); Chromatin; HeLa; Cancer research; RNA interference; Cell biology; Transcriptional regulation; Gene; Cell culture; Gene expression; Signal transduction; RNA; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000057226,0.0002487632,0.0001346034,0.0001323451,0.00009640917,0.0001843537,0.00009185644,0.0001048614,0.001323244],"category_scores_gemma":[0.00008835523,0.00009692002,0.0001857324,0.0001040223,0.0001653266,0.00008274329,0.0001885575,0.0002508563,0.0003189885],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002644531,"about_ca_system_score_gemma":0.0001625819,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009137749,"about_ca_topic_score_gemma":0.001153129,"domain_scores_codex":[0.999922,0.00001105662,0.00000489858,0.00001923597,0.00002018452,0.0000225974],"domain_scores_gemma":[0.999957,0.00001035764,0.00001006508,0.000006333019,0.000003169559,0.0000131349],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005326047,0.00000721635,0.0001992894,0.0000139099,0.000001991988,0.00003326007,0.000007653218,0.00003808987,0.9990484,0.0000687207,0.00002785874,0.0005002085],"study_design_scores_gemma":[0.000009246513,0.00006805171,0.007540745,0.000005182779,0.000005608636,0.0002469197,0.00002195315,0.001094254,0.9879772,0.00003831572,0.002988764,0.000003656974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951192,0.0005735385,0.002294008,0.00004690127,0.00001324649,0.00001638143,0.0007233458,0.00007043045,0.001142889],"genre_scores_gemma":[0.9943199,0.0002681823,0.001674556,0.00003368097,0.000005238045,0.00002076094,0.001785397,0.0000202893,0.001872024],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001323244,"threshold_uncertainty_score":0.004426718,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05140725748138842,"score_gpt":0.3477792894906255,"score_spread":0.2963720320092371,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}