{"id":"W2003134884","doi":"10.1080/713853957","title":"Combined Effects of Tumor Promoters and Serum on Proliferin mRNA Induction: A Biomarker Sensitive to Saccharin, 2,3,7,8-Tcdd, and Other Compounds at Minimal Concentrations Promoting C3H/10T1/2 Cell Transformation","year":2003,"lang":"en","type":"article","venue":"Journal of Toxicology and Environmental Health","topic":"Molecular Biology Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"","keywords":"Promoter; Acetaldehyde; Saccharin; Chemistry; Molecular biology; Messenger RNA; Gene expression; Biology; Internal medicine; Biochemistry; Endocrinology; Ethanol; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002196051,0.0004380374,0.000276608,0.0002720371,0.0001351667,0.000283678,0.0001234101,0.0002385506,0.0006716823],"category_scores_gemma":[0.000201451,0.0001470029,0.0002655689,0.0002111943,0.0003019509,0.0001831248,0.0002506497,0.0004165249,0.0002348459],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000359504,"about_ca_system_score_gemma":0.0003782787,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000975911,"about_ca_topic_score_gemma":0.002561027,"domain_scores_codex":[0.9997074,0.0000526433,0.00002471251,0.00006697854,0.00008904436,0.00005925945],"domain_scores_gemma":[0.9997522,0.0000582532,0.00006010603,0.00002931394,0.00004528767,0.00005482956],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007099709,0.000008276438,0.0002202472,0.000006033124,0.000001456479,0.000007925651,0.000007263317,0.00001250606,0.9994367,0.000003570695,0.000002835586,0.000222304],"study_design_scores_gemma":[0.000001942143,0.0002089159,0.002847114,8.409869e-7,0.000003999296,0.00002530119,0.00001166333,0.0001074534,0.9966313,0.000004039895,0.0001558101,0.000001529952],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957958,0.0007240748,0.0024547,0.00004562677,0.00001657067,0.00002811767,0.0002835611,0.0000635657,0.0005879269],"genre_scores_gemma":[0.9931847,0.0005056276,0.003345449,0.00005858822,0.00001114899,0.00006728688,0.0007491501,0.00001708025,0.002060919],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000975911,"threshold_uncertainty_score":0.002608418,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007612657658720662,"score_gpt":0.2466363695597709,"score_spread":0.2390237119010503,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}