{"id":"W2003135973","doi":"10.1182/blood-2005-07-2903","title":"A novel form of immune signaling revealed by transmission of the inflammatory mediator serotonin between dendritic cells and T cells","year":2005,"lang":"en","type":"article","venue":"Blood","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":221,"is_retracted":false,"has_abstract":true,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"National Institute of Allergy and Infectious Diseases; Amgen","keywords":"Cell biology; Immune system; T cell; Dendritic cell; Biology; Antigen-presenting cell; Inflammation; Exocytosis; Chemistry; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000847593,0.0002245045,0.0002173355,0.0001762391,0.0002274082,0.0005604834,0.0002353756,0.000648537,0.001185728],"category_scores_gemma":[0.0001123142,0.0001385389,0.0002330745,0.0001448323,0.0004234998,0.0005066627,0.0003150747,0.0005016145,0.0003493383],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003111208,"about_ca_system_score_gemma":0.0001353806,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002254538,"about_ca_topic_score_gemma":0.0002666619,"domain_scores_codex":[0.9998583,0.00002007313,0.000007458154,0.00004560106,0.00003490904,0.00003360908],"domain_scores_gemma":[0.9999565,0.000008328072,0.00001030879,0.000008940289,0.000007682633,0.000008331073],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001126094,0.00001000917,0.0004720314,0.0001278585,0.0000137052,0.0007710164,0.00006524283,0.00006852907,0.9861442,0.003217322,0.0002392696,0.008758166],"study_design_scores_gemma":[0.00003271465,0.0005090418,0.008787668,0.00003895364,0.00005737073,0.004945912,0.0001803099,0.001712491,0.953136,0.00264329,0.02793038,0.00002577646],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8524001,0.03806961,0.08079675,0.001793868,0.0006824166,0.0001185008,0.0008563186,0.0007090182,0.02457342],"genre_scores_gemma":[0.9797593,0.005359317,0.01032294,0.0004173155,0.0001213483,0.00002979548,0.0001546097,0.00001858599,0.003816783],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001185728,"threshold_uncertainty_score":0.00396663,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004993972683529228,"score_gpt":0.196800959646391,"score_spread":0.1918069869628617,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}