{"id":"W2003168287","doi":"10.1016/s0040-4039(00)00050-2","title":"Efficient coupling and solid-phase synthesis of steroidal ketone derivative using polymer-bound glycerol","year":2000,"lang":"en","type":"article","venue":"Tetrahedron Letters","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Wilfrid Laurier University","funders":"Medical Research Council","keywords":"Chemistry; Yield (engineering); Ketone; Glycerol; Solid-phase synthesis; Derivative (finance); Acetal; Coupling (piping); Phase (matter); Sequence (biology); Coupling reaction; Polymer; Combinatorial chemistry; Organic chemistry; Catalysis; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001036742,0.0001748867,0.0002652738,0.00004777954,0.00008173443,0.0000227744,0.0001144242,0.00008605348,0.0001563852],"category_scores_gemma":[0.00003350684,0.0001645589,0.0001207941,0.0001036329,0.0002021928,0.000002765914,0.00003996435,0.00006267759,0.000002605907],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002208056,"about_ca_system_score_gemma":0.0000152817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007327948,"about_ca_topic_score_gemma":0.000003166146,"domain_scores_codex":[0.9989679,0.00002475871,0.0002698259,0.0003403302,0.0001489502,0.0002481827],"domain_scores_gemma":[0.9995349,0.0000443753,0.00009182851,0.0002218912,0.00002014678,0.00008687106],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001163539,0.0001121751,0.0004074552,0.00001960207,0.0001193703,0.000003106044,0.00003866521,0.00176688,0.9910455,0.000001293075,0.00002768816,0.006341929],"study_design_scores_gemma":[0.0004700095,0.00006069252,0.0002232799,0.00003645236,0.00009961559,0.000008056517,0.00005178639,0.009507667,0.9892097,0.000001159636,0.0001369479,0.0001946629],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982724,0.0005338055,0.0007573407,0.0002417799,0.00001678338,0.00007315289,0.00002493442,0.00000885922,0.00007093395],"genre_scores_gemma":[0.9992296,0.00004438269,0.0002782725,0.0002861188,0.00009105051,0.000005312165,0.00001058884,0.00002158249,0.00003311069],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007740787,"threshold_uncertainty_score":0.6710516,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009568295438934895,"score_gpt":0.2787413039427096,"score_spread":0.2691730085037747,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}