{"id":"W2003179893","doi":"10.1093/nar/gkr030","title":"Structure of p300 bound to MEF2 on DNA reveals a mechanism of enhanceosome assembly","year":2011,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; McGill University; National Heart, Lung, and Blood Institute; National Natural Science Foundation of China; National Cancer Institute; National Institutes of Health; National Science Foundation","keywords":"Biology; Mef2; Enhancer; Transcription factor; Genetics; Transcription (linguistics); DNA; DNA-binding protein; Cell biology; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007570987,0.0003428357,0.0002824598,0.0001329438,0.0004216372,0.0004563435,0.000519195,0.0004557562,0.001618436],"category_scores_gemma":[0.0002264344,0.0002808815,0.0002511983,0.000197903,0.0003173357,0.0004020454,0.0002370745,0.00108543,0.0003501886],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007440069,"about_ca_system_score_gemma":0.0003391985,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002330836,"about_ca_topic_score_gemma":0.002396449,"domain_scores_codex":[0.9999416,0.000005035072,0.000001825766,0.00001637645,0.00002071536,0.00001442884],"domain_scores_gemma":[0.9999273,0.00001571726,0.00001450586,0.000007429109,0.00000869567,0.00002637724],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005834684,0.0002074471,0.002554982,0.0001526946,0.00005920829,0.001147542,0.0001781833,0.005104836,0.9819633,0.002202635,0.001287224,0.004558516],"study_design_scores_gemma":[0.0004593874,0.0008429195,0.05257691,0.00005183504,0.00009820197,0.002157683,0.0003953967,0.1603321,0.7647322,0.004052884,0.0141604,0.0001400756],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896309,0.0007654252,0.005866517,0.0003199036,0.00002746135,0.00001960511,0.0002107955,0.0002006351,0.002958734],"genre_scores_gemma":[0.9948526,0.0002413569,0.002602679,0.00007873548,0.000007898348,0.00001498297,0.0005658816,0.00002512815,0.001610765],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002330836,"threshold_uncertainty_score":0.005414248,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02987221054777155,"score_gpt":0.3064722882455694,"score_spread":0.2766000776977978,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}