{"id":"W2003183846","doi":"10.1021/bi015572q","title":"The Sequence-Specific Association of the ETS Domain of Murine PU.1 with DNA Exhibits Unusual Energetics","year":2002,"lang":"en","type":"article","venue":"Biochemistry","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry; Energetics; DNA; Crystallography; Dissociation (chemistry); Dissociation constant; Physical chemistry; Biochemistry; Biology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001181735,0.0001772291,0.0001544675,0.0001783376,0.0001456649,0.0002398494,0.0002131398,0.0002022869,0.0005600938],"category_scores_gemma":[0.0003258245,0.0001615501,0.000124944,0.0001301129,0.0002419203,0.0002106521,0.0002123592,0.0002936569,0.0001317458],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002168015,"about_ca_system_score_gemma":0.00006485471,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000181369,"about_ca_topic_score_gemma":0.0002022671,"domain_scores_codex":[0.9998682,0.00002163633,0.000005814814,0.00004015326,0.00003820665,0.00002588912],"domain_scores_gemma":[0.9998801,0.0000283522,0.0000453737,0.00001234234,0.00001276621,0.00002109168],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005184242,0.00001083752,0.002003198,0.00001544318,0.000006299218,0.00003615152,0.00001962856,0.0003262766,0.9966594,0.0001077261,0.00001581323,0.0007473793],"study_design_scores_gemma":[0.000009433401,0.0002132798,0.06382283,0.000006275262,0.00001542716,0.0008680541,0.00004651988,0.005359305,0.9282888,0.000324887,0.001029302,0.00001605403],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987767,0.0001764546,0.0008004577,0.0000146503,0.000001666749,0.000001542404,0.00002654694,0.0000128451,0.0001891179],"genre_scores_gemma":[0.999193,0.00004663895,0.0004165932,0.00000994642,0.000002076466,0.000004071296,0.00009005132,0.000006582589,0.0002312388],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005600938,"threshold_uncertainty_score":0.001873732,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007978312024697877,"score_gpt":0.1949151170103175,"score_spread":0.1869368049856197,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}