{"id":"W2003188806","doi":"10.1074/jbc.m113.465963","title":"Base-modified Donor Analogues Reveal Novel Dynamic Features of a Glycosyltransferase","year":2013,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Engineering and Physical Sciences Research Council; Medical Research Council; DanScatt; Danmarks Frie Forskningsfond","keywords":"Glycosyltransferase; Biochemistry; Enzyme; Chemistry; Glycosylation; Proteases; Kinase; Active site; Biology; Stereochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000104811,0.0002053628,0.0001579144,0.00006820008,0.00005496135,0.000162412,0.0001909418,0.0002242104,0.0007759687],"category_scores_gemma":[0.0001394611,0.00008277548,0.0001412024,0.00007481455,0.0001276815,0.0001585214,0.00009468365,0.0004238993,0.0001364203],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001505798,"about_ca_system_score_gemma":0.00007099922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002747738,"about_ca_topic_score_gemma":0.0002750808,"domain_scores_codex":[0.9999354,0.00001069356,0.000004435216,0.00001551899,0.00001991656,0.00001402776],"domain_scores_gemma":[0.9999279,0.00001622222,0.00002448321,0.00001181398,0.000008451414,0.00001121625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001041682,0.00002046913,0.0001101659,0.00001337357,0.00000504295,0.00003806203,0.000008685974,0.0002002676,0.9981573,0.0001108848,0.00001712288,0.001214527],"study_design_scores_gemma":[0.0000115909,0.0004325811,0.0008094054,0.000001601416,0.000008311118,0.00013595,0.000005449182,0.0008730336,0.9968842,0.00003603405,0.0007977285,0.000004067106],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957473,0.0006316964,0.00239944,0.000026691,0.000008320868,0.00001085857,0.00008699003,0.00003071611,0.001057993],"genre_scores_gemma":[0.9974126,0.0002744107,0.001436776,0.00002788298,0.000002881244,0.000007340916,0.0001374924,0.00001263743,0.0006881384],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007759687,"threshold_uncertainty_score":0.002595842,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0208489852261261,"score_gpt":0.2774423629090612,"score_spread":0.2565933776829351,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}