{"id":"W2003211588","doi":"10.1038/nbt.1788","title":"Generation of anterior foregut endoderm from human embryonic and induced pluripotent stem cells","year":2011,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":391,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ontario Institute for Cancer Research","funders":"National Institute on Aging","keywords":"Endoderm; Induced pluripotent stem cell; Biology; Embryonic stem cell; Cell biology; Stem cell; Foregut; Cellular differentiation; Anatomy; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003568242,0.000284636,0.000265696,0.0003210133,0.0002965992,0.0003256065,0.0003166654,0.000360903,0.002629472],"category_scores_gemma":[0.0001680881,0.0002924739,0.0003742752,0.0001664617,0.0001405116,0.0001969438,0.0004103919,0.0008222883,0.001336287],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001337795,"about_ca_system_score_gemma":0.0002429077,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002845228,"about_ca_topic_score_gemma":0.0007368722,"domain_scores_codex":[0.9998597,0.00001456144,0.0000225939,0.00002168467,0.00005848465,0.00002290182],"domain_scores_gemma":[0.9998772,0.00002448596,0.0000160455,0.0000277394,0.00002466815,0.00002983512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005962458,0.00001631805,0.0002097045,0.00005154643,0.000005995447,0.0001092021,0.00002744263,0.00006572474,0.9956097,0.0006311193,0.0001755262,0.003038151],"study_design_scores_gemma":[0.00004061726,0.0001114759,0.004257741,0.00001246972,0.00003157112,0.0005586582,0.00002490043,0.001012051,0.9727784,0.0002062013,0.02095469,0.00001123809],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8457531,0.003865977,0.1166263,0.0006928282,0.0006813951,0.001809029,0.01063986,0.0005899888,0.01934165],"genre_scores_gemma":[0.869352,0.003075373,0.08810713,0.0003149829,0.00009700013,0.0006424609,0.01116215,0.0001628208,0.02708604],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002629472,"threshold_uncertainty_score":0.008796394,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03415710805227472,"score_gpt":0.2673115264546517,"score_spread":0.233154418402377,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}