{"id":"W2003217138","doi":"10.1038/onc.2010.551","title":"Cx43 suppresses mammary tumor metastasis to the lung in a Cx43 mutant mouse model of human disease","year":2010,"lang":"en","type":"article","venue":"Oncogene","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":98,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Canadian Breast Cancer Research Alliance; Breast Cancer Alliance","keywords":"DMBA; Myoepithelial cell; Mammary tumor; Biology; Metastasis; Mammary gland; Connexin; Cancer research; Carcinogenesis; Pathology; Cancer; Tumor progression; Genetically modified mouse; Mutant; Breast cancer; Internal medicine; Gap junction; Immunology; Transgene; Medicine; Intracellular; Immunohistochemistry; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003074188,0.0005918231,0.0005160897,0.0008642504,0.0004438958,0.0004193544,0.000298526,0.0005518329,0.001950276],"category_scores_gemma":[0.0002344573,0.0003123143,0.0003582709,0.0003373144,0.0005574248,0.0003296533,0.0002685056,0.0007854739,0.0003653923],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005187009,"about_ca_system_score_gemma":0.0004121482,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002280202,"about_ca_topic_score_gemma":0.003537688,"domain_scores_codex":[0.9996575,0.00007137391,0.00003507056,0.00006039567,0.0000921502,0.00008352147],"domain_scores_gemma":[0.9996299,0.00006696249,0.00009465115,0.00005500572,0.00002450107,0.000128978],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001473727,0.00006080514,0.0001574065,0.00001667275,0.00000619376,0.0001249834,0.00002207827,0.0001309002,0.9982353,0.0004354907,0.00006812522,0.0005946656],"study_design_scores_gemma":[0.00003837291,0.0003842984,0.002995191,0.000006962483,0.00002527862,0.0005625548,0.00005846084,0.001662348,0.9921677,0.0001925894,0.001899834,0.000006481237],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959519,0.0006121073,0.001356805,0.0001735613,0.00003362858,0.00002019709,0.0002920639,0.0001316389,0.001428149],"genre_scores_gemma":[0.9944096,0.00049324,0.000816287,0.0000410003,0.00001429446,0.00002580595,0.0002687652,0.00006103181,0.003869995],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002280202,"threshold_uncertainty_score":0.006524265,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01230215165033414,"score_gpt":0.2680228492401563,"score_spread":0.2557206975898222,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}