{"id":"W2003281193","doi":"10.1007/s10495-008-0210-0","title":"Death receptor-4 (DR4) expression is regulated by transcription factor NF-κB in response to etoposide treatment","year":2008,"lang":"en","type":"article","venue":"APOPTOSIS","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Transcription factor; Gene knockdown; Etoposide; NF-κB; Cell biology; Biology; Molecular biology; Protein subunit; RNA interference; Protein kinase A; Apoptosis; Kinase; Signal transduction; Chemistry; Cancer research; Biochemistry; RNA; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001698771,0.0002656423,0.0002984426,0.0003779934,0.0002355655,0.0004033073,0.0001814051,0.000277012,0.00227942],"category_scores_gemma":[0.0002014476,0.0002115426,0.0002711466,0.0003009341,0.000274128,0.0003176572,0.0002480858,0.0007186562,0.0005647638],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003975092,"about_ca_system_score_gemma":0.0002215885,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005372812,"about_ca_topic_score_gemma":0.0006578501,"domain_scores_codex":[0.9997672,0.00004239271,0.00002147227,0.00003058162,0.00004675672,0.0000915631],"domain_scores_gemma":[0.9998696,0.00002152064,0.00003926613,0.00001453554,0.00001735939,0.00003777632],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009373995,0.00004730906,0.0004829644,0.00003338431,0.00001005067,0.0001289781,0.0000191686,0.00005782243,0.9973581,0.0001190904,0.00005738673,0.000748209],"study_design_scores_gemma":[0.00005808434,0.0002572481,0.01195623,0.000007402611,0.00002129933,0.0004221368,0.0001220072,0.0009709771,0.9844158,0.0001227629,0.001637591,0.000008397991],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957703,0.001279723,0.001168635,0.000110886,0.00004092545,0.00001659427,0.000321236,0.0000424919,0.0012491],"genre_scores_gemma":[0.991772,0.0009335903,0.001264103,0.00006222208,0.00001712603,0.00004580292,0.0008672802,0.00001111142,0.005026738],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00227942,"threshold_uncertainty_score":0.007625461,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01755652570519991,"score_gpt":0.2465126098156151,"score_spread":0.2289560841104152,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}