{"id":"W2003307011","doi":"10.1016/j.bbrc.2011.09.068","title":"MicroRNA-binding is required for recruitment of human Argonaute 2 to stress granules and P-bodies","year":2011,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Alberta Innovates - Health Solutions","keywords":"Argonaute; Cell biology; RNA; Biology; RNA interference; RasiRNA; Cytoplasm; microRNA; Stress granule; RNA-induced silencing complex; Gene silencing; Effector; P-bodies; RNA-binding protein; RNA silencing; Small interfering RNA; Piwi-interacting RNA; Small RNA; Messenger RNA; Translation (biology); Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004098829,0.0004033078,0.0005746388,0.000271121,0.0007689229,0.0007569469,0.0005258436,0.0007920736,0.002584228],"category_scores_gemma":[0.000864759,0.0007887385,0.0005375794,0.0001596351,0.0004374266,0.0004243659,0.0007589697,0.0008291261,0.001755122],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006341113,"about_ca_system_score_gemma":0.000420118,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007170943,"about_ca_topic_score_gemma":0.002233896,"domain_scores_codex":[0.9994143,0.0001126728,0.00007383357,0.0001492773,0.0001554537,0.00009438379],"domain_scores_gemma":[0.9992923,0.0002081792,0.0001619675,0.00008950858,0.0000538251,0.0001941993],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002523572,0.00002804728,0.0003099334,0.00002032722,0.000007141162,0.0001684802,0.00001597179,0.00003985452,0.9983773,0.0001148055,0.000137794,0.0005279868],"study_design_scores_gemma":[0.00006033282,0.0001282301,0.01919088,0.000008293528,0.00001509883,0.001124375,0.00004255333,0.002714763,0.9744903,0.0001930004,0.002011695,0.00002047987],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897698,0.001222579,0.006472724,0.0002577084,0.0001397858,0.00003933549,0.0004148098,0.0003852952,0.001297872],"genre_scores_gemma":[0.9932817,0.0001135896,0.003864548,0.0001397153,0.00002140223,0.00003919828,0.0009388953,0.0001222461,0.001478526],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002584228,"threshold_uncertainty_score":0.008645058,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2328138972406667,"score_gpt":0.4251874188120898,"score_spread":0.1923735215714232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}