{"id":"W2003338804","doi":"10.1371/journal.pone.0088980","title":"Angiopoietin-1 Upregulates De Novo Expression of Il-1β and Il1-Ra, and the Exclusive Release of Il1-Ra from Human Neutrophils","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Cytokine; Chemotaxis; Receptor; Extracellular; Angiopoietin receptor; Inflammation; Innate immune system; Interleukin 8; Cell biology; Angiopoietin; Intracellular; Interleukin; Biology; Immune system; Chemistry; Immunology; Biochemistry; Cancer research; Vascular endothelial growth factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001305735,0.0001210519,0.0002451205,0.00001919992,0.00007562937,0.000009188572,0.0001240518,0.0001185835,0.00002324726],"category_scores_gemma":[0.00005408611,0.00008788538,0.00007071146,0.0000309652,0.0002870638,0.000003591251,0.0001666574,0.00004546549,4.755312e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003580369,"about_ca_system_score_gemma":0.0000135607,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007998903,"about_ca_topic_score_gemma":0.000009648823,"domain_scores_codex":[0.9992185,0.0000890961,0.0002025874,0.0002378935,0.000113205,0.0001387043],"domain_scores_gemma":[0.999352,0.00005032583,0.0001530017,0.0003158116,0.00006761004,0.00006122547],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002178471,0.0001322375,0.007143944,0.00005813139,0.0001016026,4.848536e-7,0.0001716412,0.000005380914,0.9915941,0.0001441549,0.0001023007,0.0003282201],"study_design_scores_gemma":[0.001159523,0.0001825429,0.01287479,0.0001362259,0.0001288222,0.000001291022,0.00007325559,0.00007312369,0.9844403,0.0005838093,0.0002352555,0.0001110609],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952866,0.003990867,0.0001128981,0.0001883713,0.00001205842,0.0001452761,0.00005540475,0.000004501277,0.0002039819],"genre_scores_gemma":[0.9976856,0.0008800439,0.0008817331,0.0001344409,0.0002015539,0.00001587584,0.00003674364,0.00001799717,0.0001460102],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00715375,"threshold_uncertainty_score":0.3583862,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01280486032078226,"score_gpt":0.2161228263201071,"score_spread":0.2033179659993248,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}