{"id":"W2003338804","doi":"10.1371/journal.pone.0088980","title":"Angiopoietin-1 Upregulates De Novo Expression of Il-1β and Il1-Ra, and the Exclusive Release of Il1-Ra from Human Neutrophils","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Cytokine; Chemotaxis; Receptor; Extracellular; Angiopoietin receptor; Inflammation; Innate immune system; Interleukin 8; Cell biology; Angiopoietin; Intracellular; Interleukin; Biology; Immune system; Chemistry; Immunology; Biochemistry; Cancer research; Vascular endothelial growth factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001390125,0.000341358,0.000273429,0.0002253964,0.00007881525,0.0003863081,0.00006457841,0.0001713154,0.001281586],"category_scores_gemma":[0.0001515802,0.0001690319,0.0001947277,0.0001263626,0.0002059917,0.0002453508,0.0001520345,0.0006546323,0.000339175],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001853388,"about_ca_system_score_gemma":0.0001329193,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002105152,"about_ca_topic_score_gemma":0.000334032,"domain_scores_codex":[0.9998152,0.00002797531,0.0000151421,0.00004501802,0.000043341,0.00005337393],"domain_scores_gemma":[0.9998537,0.00002899579,0.00004445362,0.00001314879,0.00001326035,0.0000463874],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001734322,0.00003210134,0.0002479387,0.00004550774,0.000002651626,0.0001238723,0.00001965867,0.00002599777,0.998108,0.0000306955,0.00003047348,0.001159686],"study_design_scores_gemma":[0.00003990839,0.001270732,0.01902477,0.00001087716,0.00002398605,0.0007049782,0.00006161524,0.0005258119,0.974358,0.00008830647,0.003884725,0.000006158219],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897524,0.005606486,0.001948441,0.0001305549,0.00009985524,0.0000730014,0.0004752072,0.00005320774,0.00186078],"genre_scores_gemma":[0.9899765,0.002915712,0.001905532,0.00013833,0.0001129526,0.00009332912,0.0005586103,0.00001092177,0.004288178],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001281586,"threshold_uncertainty_score":0.004287362,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01280486032078226,"score_gpt":0.2161228263201071,"score_spread":0.2033179659993248,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}