{"id":"W2003428612","doi":"10.1016/j.exppara.2010.02.009","title":"Cysteamine, the natural metabolite of pantetheinase, shows specific activity against Plasmodium","year":2010,"lang":"en","type":"article","venue":"Experimental Parasitology","topic":"Neurological diseases and metabolism","field":"Neuroscience","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal General Hospital; University of Toronto; Biotechnology Research Institute; Centre for Global Health Research; McGill University","funders":"Canadian Institutes of Health Research; National Institutes of Health; Ontario Genomics Institute; Genome Canada","keywords":"Cysteamine; Biology; Plasmodium chabaudi; In vivo; Infectivity; Plasmodium falciparum; Metabolite; In vitro; Parasite hosting; Biochemistry; Pharmacology; Microbiology; Virology; Immunology; Parasitemia; Malaria; Virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006664092,0.0001973744,0.0001996743,0.0001026642,0.00009554948,0.0001476194,0.0001165373,0.0001889069,0.0007170335],"category_scores_gemma":[0.0001231183,0.00008018215,0.00008359012,0.00009865175,0.0001671472,0.0001407805,0.0001228095,0.0002135755,0.0001696984],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001733943,"about_ca_system_score_gemma":0.0001694735,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004465935,"about_ca_topic_score_gemma":0.0007824054,"domain_scores_codex":[0.999956,0.00001107271,0.000003512122,0.000007812937,0.000009783726,0.00001190427],"domain_scores_gemma":[0.9999477,0.00001170661,0.00001210395,0.000006720232,0.000008660457,0.00001302351],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002929233,0.00001734438,0.0001761054,0.00005616601,0.000005650796,0.00005155327,0.000007866975,0.00002862787,0.9959393,0.00006048498,0.0000580115,0.003305992],"study_design_scores_gemma":[0.00002397618,0.0006494455,0.002822874,0.000003751997,0.0000131955,0.0006906381,0.00001009969,0.0002200146,0.9940811,0.00003533205,0.001447077,0.000002574243],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925159,0.002871171,0.001405566,0.0001321442,0.0000220936,0.00002390446,0.0001762313,0.00004522141,0.00280783],"genre_scores_gemma":[0.9970279,0.0008168889,0.0008983391,0.00002506514,0.000007227226,0.000007870949,0.0002438223,0.000004530133,0.0009683317],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007170335,"threshold_uncertainty_score":0.002398729,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0237089409348827,"score_gpt":0.3122552714760978,"score_spread":0.2885463305412151,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}