{"id":"W2003428612","doi":"10.1016/j.exppara.2010.02.009","title":"Cysteamine, the natural metabolite of pantetheinase, shows specific activity against Plasmodium","year":2010,"lang":"en","type":"article","venue":"Experimental Parasitology","topic":"Neurological diseases and metabolism","field":"Neuroscience","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal General Hospital; University of Toronto; Biotechnology Research Institute; Centre for Global Health Research; McGill University","funders":"Canadian Institutes of Health Research; National Institutes of Health; Ontario Genomics Institute; Genome Canada","keywords":"Cysteamine; Biology; Plasmodium chabaudi; In vivo; Infectivity; Plasmodium falciparum; Metabolite; In vitro; Parasite hosting; Biochemistry; Pharmacology; Microbiology; Virology; Immunology; Parasitemia; Malaria; Virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001004726,0.0002463386,0.0003769351,0.0000576564,0.0001856937,0.00002679635,0.0005895038,0.0001111081,0.0001575616],"category_scores_gemma":[0.0001604706,0.0001556033,0.0002025438,0.0001800141,0.0007889939,0.0001466115,0.000186572,0.0005196891,0.00007233918],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007229183,"about_ca_system_score_gemma":0.00002354324,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001229954,"about_ca_topic_score_gemma":0.000005332099,"domain_scores_codex":[0.998193,0.0003128505,0.000260001,0.0005331739,0.0002655638,0.0004353878],"domain_scores_gemma":[0.9987839,0.0003696581,0.0001652987,0.0005317698,0.00002190281,0.0001274231],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002760999,0.0003655523,0.0009361849,0.000002865372,0.000006128309,0.0000459613,0.00008971429,0.000002652883,0.9846635,0.01208159,0.0001496189,0.001380108],"study_design_scores_gemma":[0.0005160825,0.00009501968,0.04082342,0.000001185604,0.000008785832,0.00006854055,0.00004369843,0.00008882107,0.9453704,0.0001678624,0.01266154,0.0001546697],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920905,0.0008276132,0.000009859639,0.0002842603,0.003220865,0.0003446174,0.00005760673,0.00006277999,0.003101889],"genre_scores_gemma":[0.9983408,0.00005588032,0.00006311873,0.001078302,0.0002213892,0.00005138897,0.00000339678,0.00001887733,0.0001668752],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03988724,"threshold_uncertainty_score":0.6345319,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0237089409348827,"score_gpt":0.3122552714760978,"score_spread":0.2885463305412151,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}