{"id":"W2003442675","doi":"10.1161/01.res.0000115945.89741.22","title":"Protein Kinase A Phosphorylation at Serine-2808 of the Cardiac Ca <sup>2+</sup> -Release Channel (Ryanodine Receptor) Does Not Dissociate 12.6-kDa FK506-Binding Protein (FKBP12.6)","year":2004,"lang":"en","type":"article","venue":"Circulation Research","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":159,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research; Fondation pour la Recherche Médicale; Canada Research Chairs","keywords":"Ryanodine receptor 2; Phosphorylation; FKBP; Serine; Phosphoserine; Chemistry; Phosphorylation cascade; Biochemistry; Protein kinase A; Ryanodine receptor; Protein phosphorylation; Biology; Cell biology; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012682,0.0003655508,0.0002818045,0.000115416,0.000181118,0.0003120028,0.000289264,0.0002531663,0.002042833],"category_scores_gemma":[0.0001891091,0.0001551092,0.0003257878,0.0001204012,0.0002819203,0.0002334869,0.000195516,0.0006928355,0.0007268051],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003194953,"about_ca_system_score_gemma":0.0002508845,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007249263,"about_ca_topic_score_gemma":0.0008407668,"domain_scores_codex":[0.999797,0.0000243649,0.00003062538,0.00005823188,0.00003961242,0.00005020338],"domain_scores_gemma":[0.9998192,0.00003113785,0.00005288974,0.00003051327,0.0000160458,0.00005010644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001555334,0.00005357511,0.0002505046,0.00003041972,0.000008557184,0.00003534161,0.000009925228,0.0000361042,0.9987447,0.00008900935,0.00003521219,0.000551165],"study_design_scores_gemma":[0.00003187546,0.0002181926,0.007237337,0.000006308082,0.00001316604,0.0004013996,0.00001894535,0.001013103,0.9887303,0.00006497423,0.00225909,0.000005257512],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958656,0.0008220514,0.001615715,0.00009773498,0.0000387592,0.00001768666,0.0002487007,0.00003874372,0.001255014],"genre_scores_gemma":[0.9918494,0.0004796491,0.00266835,0.0001009073,0.00001241728,0.00004713299,0.001604793,0.00003043175,0.003206919],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002042833,"threshold_uncertainty_score":0.006833971,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02553021927485761,"score_gpt":0.2929330992520237,"score_spread":0.2674028799771661,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}