{"id":"W2003442675","doi":"10.1161/01.res.0000115945.89741.22","title":"Protein Kinase A Phosphorylation at Serine-2808 of the Cardiac Ca <sup>2+</sup> -Release Channel (Ryanodine Receptor) Does Not Dissociate 12.6-kDa FK506-Binding Protein (FKBP12.6)","year":2004,"lang":"en","type":"article","venue":"Circulation Research","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":159,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research; Fondation pour la Recherche Médicale; Canada Research Chairs","keywords":"Ryanodine receptor 2; Phosphorylation; FKBP; Serine; Phosphoserine; Chemistry; Phosphorylation cascade; Biochemistry; Protein kinase A; Ryanodine receptor; Protein phosphorylation; Biology; Cell biology; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00133355,0.0002822104,0.0005542342,0.0002781912,0.0007260101,0.00003520096,0.0001897362,0.000313575,0.000261712],"category_scores_gemma":[0.0009538112,0.0002035289,0.0004208408,0.000748277,0.0003676467,0.0001835616,0.0002186763,0.0008596601,0.0002076933],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001020728,"about_ca_system_score_gemma":0.000469096,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005970363,"about_ca_topic_score_gemma":0.0000405764,"domain_scores_codex":[0.9963374,0.0005795584,0.0005257447,0.0006143878,0.001181889,0.0007609843],"domain_scores_gemma":[0.9980969,0.000124619,0.0002147929,0.0007392733,0.0005949575,0.0002295007],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001229905,0.0001958684,0.004114235,0.0003701737,0.0002073665,0.00004966379,0.001544668,0.01620731,0.9744787,0.0005269403,0.0002806416,0.0007945403],"study_design_scores_gemma":[0.004100169,0.0005483266,0.0588297,0.0011032,0.0001245178,0.00003295628,0.0005906657,0.004498379,0.92743,0.001453464,0.0007434726,0.0005452005],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923078,0.0001798575,0.00003120767,0.003124073,0.0001279941,0.003594096,0.0001041489,0.00007185353,0.0004589223],"genre_scores_gemma":[0.9934745,0.00003688864,0.00006003553,0.00004893963,0.0004627337,0.0005240068,0.0002149215,0.00006006486,0.00511789],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05471547,"threshold_uncertainty_score":0.8299668,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02553021927485761,"score_gpt":0.2929330992520237,"score_spread":0.2674028799771661,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}