{"id":"W2003469411","doi":"10.1016/j.jaci.2011.11.033","title":"The airway epithelium nucleotide-binding domain and leucine-rich repeat protein 3 inflammasome is activated by urban particulate matter","year":2012,"lang":"en","type":"article","venue":"Journal of Allergy and Clinical Immunology","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":163,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary; St. Paul's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC; Canadian Lung Association","keywords":"Leucine-rich repeat; Inflammasome; Leucine; Chemistry; Airway; Respiratory epithelium; Particulates; Cell biology; Epithelium; Biology; Biochemistry; Amino acid; Physics; Ecology; Receptor; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002492689,0.0003442286,0.0003821034,0.0003828974,0.0003348297,0.0006135301,0.0001980099,0.0006324524,0.002892938],"category_scores_gemma":[0.0002126814,0.0002354009,0.0003949979,0.0002102548,0.0004072791,0.0003494578,0.0006874622,0.0004593758,0.0006540652],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000370203,"about_ca_system_score_gemma":0.0003199918,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005596589,"about_ca_topic_score_gemma":0.0007981022,"domain_scores_codex":[0.9997426,0.00006009835,0.00002167458,0.00003786858,0.00006363882,0.00007415489],"domain_scores_gemma":[0.9998512,0.00001228902,0.00006234577,0.00001286678,0.00001983035,0.00004146186],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002420619,0.0001395765,0.008173151,0.0001384737,0.00004925155,0.00112757,0.0000785119,0.0001629087,0.9819833,0.0005447707,0.000434331,0.004747515],"study_design_scores_gemma":[0.0005151661,0.001588048,0.3441344,0.00006357316,0.000194165,0.004745539,0.001284262,0.004986804,0.6317363,0.003532171,0.007163778,0.00005580254],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945152,0.00170565,0.001714479,0.000491237,0.0001096233,0.00003762738,0.0002643815,0.00005366792,0.001108068],"genre_scores_gemma":[0.9970304,0.0004463724,0.0004307633,0.0001003089,0.00004060255,0.00002509709,0.0002441615,0.000008573074,0.001673549],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002892938,"threshold_uncertainty_score":0.009677827,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007478960035207379,"score_gpt":0.2523933928178924,"score_spread":0.244914432782685,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}