{"id":"W2003489394","doi":"10.1016/j.jpba.2008.01.020","title":"HPLC assay with UV detection for determination of RBC purine nucleotide concentrations and application for biomarker study in vivo","year":2008,"lang":"en","type":"article","venue":"Journal of Pharmaceutical and Biomedical Analysis","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Canada; Dalhousie University","funders":"Health Canada","keywords":"Chemistry; Nucleotide; GTP'; Purine; High-performance liquid chromatography; In vivo; Chromatography; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001563323,0.001411146,0.0008945474,0.001773585,0.001342006,0.0007112934,0.0009515351,0.001637622,0.003904354],"category_scores_gemma":[0.001635216,0.0008783303,0.0005357826,0.001119563,0.0007100026,0.0007245937,0.0005486147,0.001898193,0.003442263],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006166068,"about_ca_system_score_gemma":0.002036279,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001163313,"about_ca_topic_score_gemma":0.003116282,"domain_scores_codex":[0.9985453,0.0004513852,0.0001035352,0.0003321042,0.0004661078,0.0001016014],"domain_scores_gemma":[0.9984283,0.0005927243,0.0001623855,0.0001503253,0.0005136069,0.0001527267],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003488262,0.0005511334,0.001868921,0.0002973669,0.00007352875,0.0001494046,0.0000974434,0.000214678,0.948213,0.0009077161,0.002378837,0.04489925],"study_design_scores_gemma":[0.00005720291,0.0007963183,0.003636163,0.00004280816,0.0001528711,0.001790743,0.00005562074,0.003743094,0.977024,0.0005283378,0.01210487,0.00006790662],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.1192183,0.01297384,0.8398132,0.001200756,0.001037871,0.001451735,0.001903112,0.006684231,0.01571693],"genre_scores_gemma":[0.280001,0.010701,0.6767676,0.00360553,0.0006519209,0.003097936,0.002119108,0.0004718659,0.02258406],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.003904354,"threshold_uncertainty_score":0.01306134,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02067703244311094,"score_gpt":0.3234621240673435,"score_spread":0.3027850916242326,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}