{"id":"W2003495361","doi":"10.1371/journal.pone.0025644","title":"FACT, the Bur Kinase Pathway, and the Histone Co-Repressor HirC Have Overlapping Nucleosome-Related Roles in Yeast Transcription Elongation","year":2011,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Killam Trusts; Nova Scotia Health Research Foundation; Terry Fox Foundation; Beatrice Hunter Cancer Research Institute; Cancer Research Institute","keywords":"Transcription coregulator; Nucleosome; RNA polymerase II; Biology; Transcription factor II D; Histone methylation; General transcription factor; Transcription (linguistics); Histone code; Histone; Cell biology; RNA polymerase II holoenzyme; Eukaryotic transcription; Promoter; Genetics; Molecular biology; Chromatin remodeling; Gene expression; Gene; DNA methylation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001287779,0.0006825068,0.0002204636,0.0002096369,0.0001969548,0.0004865969,0.0002744047,0.00035608,0.001121537],"category_scores_gemma":[0.0001236391,0.0003119706,0.0003116413,0.0001335616,0.0002523258,0.0002738151,0.0005490918,0.0004918395,0.0004469636],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002913917,"about_ca_system_score_gemma":0.0002534873,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003528133,"about_ca_topic_score_gemma":0.0007061175,"domain_scores_codex":[0.9998789,0.00001050136,0.00001147018,0.00003580503,0.00004096581,0.00002234267],"domain_scores_gemma":[0.9998211,0.00001976643,0.00006012904,0.00002478131,0.0000117402,0.00006249909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008406608,0.000008964165,0.0004977946,0.00003615165,0.000007777692,0.0001191309,0.000009086863,0.0001238363,0.997047,0.0002498938,0.00001537774,0.001801043],"study_design_scores_gemma":[0.00003501795,0.0002565344,0.01387715,0.0000178836,0.00004227139,0.001697593,0.00005083008,0.002051614,0.9755054,0.0003600055,0.006095748,0.000009855326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853388,0.006698635,0.005574001,0.0001225459,0.00002893872,0.00001454137,0.00033793,0.0001782741,0.001706403],"genre_scores_gemma":[0.99283,0.001599939,0.002904757,0.00003024266,0.000007085829,0.00001511097,0.0004688711,0.00002475002,0.002119213],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001121537,"threshold_uncertainty_score":0.003751934,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02033011899014037,"score_gpt":0.2032397517294811,"score_spread":0.1829096327393407,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}