{"id":"W2003507535","doi":"10.1074/jbc.m112445200","title":"Recombinant Class I Aldehyde Dehydrogenases Specific for All-trans- or 9-cis-Retinal","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôtel-Dieu de Montréal; Hôtel-Dieu de Québec; Université de Montréal","funders":"","keywords":"Aldehyde dehydrogenase; Retinal; Biochemistry; Morphogen; Retinaldehyde; Retinoic acid; ALDH2; Amino acid; Biology; Dehydrogenase; Enzyme; Chemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003232953,0.0007331452,0.00043217,0.0001715298,0.0001109436,0.0004364783,0.0004460801,0.0002873355,0.001116727],"category_scores_gemma":[0.0003292308,0.0003092796,0.0004637588,0.000313516,0.0002849599,0.0002791281,0.0002627459,0.0007611525,0.001216991],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003452624,"about_ca_system_score_gemma":0.0002642754,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005168198,"about_ca_topic_score_gemma":0.0005702551,"domain_scores_codex":[0.9995794,0.00006624348,0.00005357387,0.0001097479,0.0001040907,0.00008687295],"domain_scores_gemma":[0.9997234,0.0000484242,0.00008239372,0.0000669635,0.00004346749,0.00003541318],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007141471,0.0000141742,0.000129762,0.00002889047,0.000006958726,0.00001957954,0.00001244601,0.00005240431,0.9988334,0.00009679241,0.00002446826,0.000709717],"study_design_scores_gemma":[0.0000159945,0.0001160774,0.0007543672,0.000006312203,0.00003096159,0.000221878,0.00002181024,0.0005837776,0.9917588,0.00005412851,0.006429925,0.00000606212],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9403863,0.003313904,0.05147298,0.0002124377,0.0002085858,0.0002058055,0.001358333,0.0004628212,0.002378745],"genre_scores_gemma":[0.9365298,0.002721813,0.0395352,0.0001109961,0.00004893957,0.0001508016,0.007618141,0.0002380167,0.01304643],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001116727,"threshold_uncertainty_score":0.003735781,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04101607213610186,"score_gpt":0.2657480418100277,"score_spread":0.2247319696739258,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}