{"id":"W2003583829","doi":"10.1167/iovs.11-8418","title":"Differential Gene Expression in Eyecup and Retina of a Mouse Model of Stargardt-like Macular Dystrophy (STGD3)","year":2011,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Retina; Glial fibrillary acidic protein; Downregulation and upregulation; Biology; Retinal degeneration; Dystrophy; Macular dystrophy; Photoreceptor cell; Genetically modified mouse; Retinal; Molecular biology; Cell biology; Transgene; Immunology; Immunohistochemistry; Gene; Genetics; Neuroscience; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001724516,0.000446051,0.0003624116,0.001036051,0.0001896105,0.000331429,0.0001176102,0.0004716464,0.0008095225],"category_scores_gemma":[0.0001235965,0.00023074,0.000345968,0.0002924984,0.0003534381,0.0002546362,0.0001659522,0.0004501748,0.0002223877],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004289729,"about_ca_system_score_gemma":0.0002223786,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006155358,"about_ca_topic_score_gemma":0.001127767,"domain_scores_codex":[0.9997577,0.00001743848,0.0000158944,0.00007135507,0.00008656109,0.00005112918],"domain_scores_gemma":[0.9997388,0.00002086007,0.000104672,0.0000170858,0.00004028045,0.00007834184],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002232891,0.00002237441,0.001082861,0.00002774798,0.000006731342,0.0001389853,0.00002319738,0.00001336857,0.9979702,0.00001840032,0.00001433207,0.0004584797],"study_design_scores_gemma":[0.00005224866,0.001246923,0.1479519,0.00001811561,0.00008385531,0.001963537,0.0001754033,0.0006172496,0.8464054,0.00007957416,0.001392866,0.0000129287],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978201,0.0006640081,0.000541397,0.00002897525,0.00000827073,0.00001753923,0.0004532276,0.00004637175,0.0004199733],"genre_scores_gemma":[0.9925658,0.0007421456,0.001803005,0.00007156719,0.000007085281,0.00009293839,0.0009984066,0.00003381507,0.00368529],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001036051,"threshold_uncertainty_score":0.003112435,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03067872514407211,"score_gpt":0.2831286482347378,"score_spread":0.2524499230906657,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}