{"id":"W2003583829","doi":"10.1167/iovs.11-8418","title":"Differential Gene Expression in Eyecup and Retina of a Mouse Model of Stargardt-like Macular Dystrophy (STGD3)","year":2011,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Retina; Glial fibrillary acidic protein; Downregulation and upregulation; Biology; Retinal degeneration; Dystrophy; Macular dystrophy; Photoreceptor cell; Genetically modified mouse; Retinal; Molecular biology; Cell biology; Transgene; Immunology; Immunohistochemistry; Gene; Genetics; Neuroscience; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002222547,0.000161942,0.0002256315,0.0001281595,0.00006094122,0.000005516202,0.0002899257,0.0001198342,0.00002202542],"category_scores_gemma":[0.000127184,0.0001409845,0.00003930998,0.0002070822,0.002623254,0.00001602999,0.0003152475,0.00008426929,7.395822e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000011067,"about_ca_system_score_gemma":0.0001852424,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000577095,"about_ca_topic_score_gemma":0.000002222707,"domain_scores_codex":[0.9986811,0.00008469086,0.0002956979,0.0004561374,0.0002122316,0.0002701731],"domain_scores_gemma":[0.9993886,0.000009008422,0.0001762485,0.0001796255,0.0001267609,0.0001197908],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001461334,0.00009837467,0.05998819,0.00001789137,0.000007498529,0.000006350571,0.0005524028,0.00001957203,0.93909,0.00004307506,0.00000512562,0.00002535566],"study_design_scores_gemma":[0.0003730862,0.000539524,0.03851066,0.00002319925,0.000005988296,0.00001037238,0.000134569,0.0005204488,0.9586981,0.001040544,0.000001161845,0.0001423259],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990665,0.00008527262,0.0001317665,0.000008587858,0.00004017432,0.0001602308,0.00001148196,0.000003138911,0.0004928286],"genre_scores_gemma":[0.9918388,0.00002965752,0.007966282,0.00001994985,0.000006511212,0.00001339261,0.00001234625,0.000009254009,0.0001037872],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02147753,"threshold_uncertainty_score":0.9665489,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03067872514407211,"score_gpt":0.2831286482347378,"score_spread":0.2524499230906657,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}