{"id":"W2003589118","doi":"10.1182/blood-2004-10-4065","title":"Human embryonic stem cells maintained in the absence of mouse embryonic fibroblasts or conditioned media are capable of hematopoietic development","year":2005,"lang":"en","type":"article","venue":"Blood","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":170,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Haematopoiesis; Embryonic stem cell; Cell biology; Biology; Embryoid body; Basic fibroblast growth factor; Stem cell; Hemangioblast; Germ layer; Immunology; Molecular biology; Adult stem cell; Growth factor; Genetics; Induced pluripotent stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003140012,0.0004111696,0.0002957529,0.0002122437,0.0001739275,0.0003251031,0.0002656002,0.0002175538,0.002229505],"category_scores_gemma":[0.0002311441,0.0001529448,0.0001579312,0.0002060341,0.0001930272,0.0002030808,0.0002617432,0.0003214173,0.001648007],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001146772,"about_ca_system_score_gemma":0.0002523164,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000253641,"about_ca_topic_score_gemma":0.0008402342,"domain_scores_codex":[0.9997635,0.00003486501,0.00004991288,0.00003873501,0.00009606637,0.00001689745],"domain_scores_gemma":[0.9998555,0.0000335994,0.00003043135,0.00003965273,0.00002244911,0.00001842199],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004705137,0.00001997164,0.0004636451,0.00005896878,0.000006865381,0.00009334795,0.00002788661,0.00002861951,0.9942716,0.000265431,0.0001666268,0.00454998],"study_design_scores_gemma":[0.00001376174,0.0001503918,0.005485331,0.00002314522,0.00003312398,0.0007590373,0.00003152241,0.0002294574,0.968667,0.0001502056,0.02444783,0.000009155541],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9167478,0.01387257,0.04620351,0.0003043624,0.0003841264,0.0004986738,0.005377373,0.0008359956,0.01577559],"genre_scores_gemma":[0.8986372,0.01277906,0.04867519,0.0002012233,0.00007753676,0.0003739022,0.01341643,0.0001132054,0.02572616],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002229505,"threshold_uncertainty_score":0.007458448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01556145250753862,"score_gpt":0.250030536068108,"score_spread":0.2344690835605694,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}