{"id":"W2003589118","doi":"10.1182/blood-2004-10-4065","title":"Human embryonic stem cells maintained in the absence of mouse embryonic fibroblasts or conditioned media are capable of hematopoietic development","year":2005,"lang":"en","type":"article","venue":"Blood","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":170,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Haematopoiesis; Embryonic stem cell; Cell biology; Biology; Embryoid body; Basic fibroblast growth factor; Stem cell; Hemangioblast; Germ layer; Immunology; Molecular biology; Adult stem cell; Growth factor; Genetics; Induced pluripotent stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003994993,0.0001586786,0.000242052,0.00008583163,0.00006200477,0.00001161448,0.0004651026,0.0001234571,0.00005913484],"category_scores_gemma":[0.00002519981,0.0001186873,0.00006594705,0.0001765894,0.0001229105,0.000005882443,0.0001362852,0.0001154463,0.00002050751],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000240578,"about_ca_system_score_gemma":0.000212098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000109229,"about_ca_topic_score_gemma":0.0004104282,"domain_scores_codex":[0.9985123,0.0001296236,0.0003828791,0.0002892833,0.0003486864,0.0003372702],"domain_scores_gemma":[0.9991403,0.00004726611,0.0001979822,0.0004541431,0.0000982475,0.00006203806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003704214,0.0004979414,0.0009300752,0.0002221803,0.00005313757,0.00001364668,0.0003623415,0.0001960438,0.9971434,0.00004535528,0.000457731,0.00004113981],"study_design_scores_gemma":[0.001558838,0.0001414052,0.003446765,0.00009347349,0.0000119186,0.00002025065,0.0007346857,0.000014295,0.9934049,0.000009754935,0.0004241559,0.0001396067],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998893,0.0003872578,0.00003483122,0.0000981978,0.00001580403,0.0003444701,0.00003058393,0.000006252099,0.0001895943],"genre_scores_gemma":[0.9977198,0.00005104288,0.0004214553,0.00003988625,0.00003487778,0.00004364381,0.00004320602,0.00001926962,0.001626794],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003738514,"threshold_uncertainty_score":0.4839929,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01556145250753862,"score_gpt":0.250030536068108,"score_spread":0.2344690835605694,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}