{"id":"W2003646873","doi":"10.1093/emboj/cdg053","title":"ATP binding by glutamyl‐tRNA synthetase is switched to the productive mode by tRNA binding","year":2003,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":157,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"RIKEN","keywords":"Biology; Transfer RNA; Binding site; Biochemistry; Genetics; RNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004143217,0.0005066079,0.0005704443,0.0001979385,0.0004798511,0.001541398,0.0007019172,0.0007406866,0.003472081],"category_scores_gemma":[0.0009388599,0.0005278569,0.0003119209,0.0001908268,0.0005726707,0.000859753,0.0007970702,0.00103656,0.002412588],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000604353,"about_ca_system_score_gemma":0.0003926535,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003176093,"about_ca_topic_score_gemma":0.0004918744,"domain_scores_codex":[0.9996293,0.0000572782,0.00003231971,0.00009292276,0.00008532401,0.0001028874],"domain_scores_gemma":[0.9995366,0.0001417825,0.00005612809,0.00008458365,0.00004551967,0.0001354439],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008709611,0.00006032453,0.0005509068,0.00006975653,0.00001149659,0.0004363839,0.0000690376,0.0001530702,0.9882733,0.002879891,0.0003908614,0.006233986],"study_design_scores_gemma":[0.0000710172,0.0001275965,0.001950141,0.00001495058,0.00001151775,0.0004342083,0.00009164726,0.002263934,0.9896392,0.001791001,0.003581793,0.00002295989],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.977674,0.002538548,0.01199188,0.0005158804,0.0003512284,0.00002667927,0.000105814,0.0007005038,0.006095436],"genre_scores_gemma":[0.9956221,0.0003114514,0.001300304,0.0001013896,0.00002076712,0.00001022645,0.0001549736,0.00008741959,0.002391413],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003472081,"threshold_uncertainty_score":0.01161528,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01191481804080623,"score_gpt":0.2507500756662548,"score_spread":0.2388352576254485,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}