{"id":"W2003675091","doi":"10.1074/jbc.m110.171728","title":"Synthesis, Maturation, and Trafficking of Human Na+-Dicarboxylate Cotransporter NaDC1 Requires the Chaperone Activity of Cyclophilin B","year":2011,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Cyclophilin; Calcineurin; Reabsorption; HEK 293 cells; Symporter; Chemistry; Cell biology; Biochemistry; Apical membrane; Biology; Kidney; Transporter; Transplantation; Receptor; Internal medicine; Endocrinology; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000876631,0.0001020604,0.0001238694,0.00007460096,0.0001423942,0.0002484043,0.00009444433,0.0001379946,0.0008509097],"category_scores_gemma":[0.000120323,0.00008937993,0.0001297311,0.00008193737,0.00009877468,0.00009299567,0.00009817175,0.0002444252,0.0003015087],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003259665,"about_ca_system_score_gemma":0.0002303068,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001891291,"about_ca_topic_score_gemma":0.00281243,"domain_scores_codex":[0.9999214,0.00001045731,0.000008474054,0.00002394713,0.00001734359,0.00001829183],"domain_scores_gemma":[0.9999497,0.000009428708,0.000008667507,0.000007613307,0.000007873256,0.00001674881],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008722974,0.000009280922,0.0002828891,0.00001423496,0.000002411278,0.00002896423,0.000008098902,0.00002648307,0.9988569,0.00005951644,0.00004306826,0.0005809261],"study_design_scores_gemma":[0.00002199415,0.00007976317,0.01698071,0.000003578035,0.0000128519,0.000250965,0.00003017147,0.001601324,0.9775465,0.00002981433,0.003438355,0.000003906257],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966714,0.0009620779,0.001114515,0.0001219978,0.00001672538,0.00001365854,0.0003097322,0.00002137739,0.0007684294],"genre_scores_gemma":[0.9957607,0.0006324893,0.001037162,0.0000509407,0.000007136479,0.00001701214,0.0007573801,0.00001318114,0.001723903],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001891291,"threshold_uncertainty_score":0.003760636,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03570080358484594,"score_gpt":0.253248483976366,"score_spread":0.2175476803915201,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}