{"id":"W2003696704","doi":"10.1016/j.jpeds.2013.02.040","title":"Autosomal Dominant Cases of Chronic Mucocutaneous Candidiasis Segregates with Mutations of Signal Transducer and Activator of Transcription 1, But Not of Toll-Like Receptor 3","year":2013,"lang":"en","type":"article","venue":"The Journal of Pediatrics","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"CSL Behring","keywords":"Chronic mucocutaneous candidiasis; Medicine; STAT protein; STAT1; Mucocutaneous zone; Immunology; Fluconazole; Activator (genetics); Transcription (linguistics); Virology; Receptor; Gene; Biology; STAT3; Genetics; Dermatology; Pathology; Internal medicine; Antifungal","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003005486,0.0001393051,0.0004611466,0.000181417,0.00008193569,0.000003574741,0.000195618,0.0001209857,0.0002066727],"category_scores_gemma":[0.00004906338,0.00008704273,0.0001251933,0.0002110043,0.0004998153,0.0001682522,0.00001208444,0.0002283517,0.000001322756],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002342356,"about_ca_system_score_gemma":0.0002968432,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007289835,"about_ca_topic_score_gemma":0.00001603216,"domain_scores_codex":[0.9987509,0.0001789823,0.0007142101,0.00007656679,0.0001037659,0.0001756267],"domain_scores_gemma":[0.9981341,0.0004791456,0.000923792,0.000127273,0.0003252953,0.00001040846],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009916394,0.0002916042,0.0003721359,0.000258922,0.0001158372,0.00000235563,0.004337554,0.0002626844,0.9895002,0.00002825219,0.0000256563,0.003813126],"study_design_scores_gemma":[0.002357144,0.002712715,0.005133718,0.0001034326,0.0007676799,0.0006072965,0.00611139,0.0000159943,0.981952,0.00004029274,0.00006367301,0.0001347387],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9802969,0.01884915,0.000260438,0.0001153088,0.0001818285,0.0001858502,0.00009393922,0.000002790071,0.00001386787],"genre_scores_gemma":[0.9974004,0.002446884,0.00006283054,0.000006334645,0.00001035883,0.00000207926,0.000006701924,0.00001091807,0.00005347839],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01710359,"threshold_uncertainty_score":0.35495,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007156525535701411,"score_gpt":0.2012050708327751,"score_spread":0.1940485452970737,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}