{"id":"W2003696704","doi":"10.1016/j.jpeds.2013.02.040","title":"Autosomal Dominant Cases of Chronic Mucocutaneous Candidiasis Segregates with Mutations of Signal Transducer and Activator of Transcription 1, But Not of Toll-Like Receptor 3","year":2013,"lang":"en","type":"article","venue":"The Journal of Pediatrics","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"CSL Behring","keywords":"Chronic mucocutaneous candidiasis; Medicine; STAT protein; STAT1; Mucocutaneous zone; Immunology; Fluconazole; Activator (genetics); Transcription (linguistics); Virology; Receptor; Gene; Biology; STAT3; Genetics; Dermatology; Pathology; Internal medicine; Antifungal","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004552221,0.004435174,0.0009987977,0.002308521,0.002109218,0.001013433,0.0008490454,0.002178482,0.005619083],"category_scores_gemma":[0.001783816,0.0008658123,0.0006565621,0.002537348,0.001562045,0.000486888,0.0009945381,0.0009224605,0.0009613438],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005295401,"about_ca_system_score_gemma":0.0008149054,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00296258,"about_ca_topic_score_gemma":0.00508959,"domain_scores_codex":[0.9990332,0.0001353072,0.00009248731,0.0002141006,0.0002670284,0.0002578134],"domain_scores_gemma":[0.9986262,0.0004567295,0.0004318236,0.00009474352,0.00008888556,0.0003015592],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"observational","study_design_scores_codex":[0.001405193,0.000243307,0.1563991,0.0001923341,0.0002089609,0.7195292,0.0007323108,0.0002043174,0.1107443,0.001321891,0.001159493,0.007859539],"study_design_scores_gemma":[0.00009665575,0.000150944,0.1040988,0.00005816541,0.0001589286,0.8874726,0.0002795339,0.0003283406,0.00596376,0.0002732727,0.001090245,0.00002877307],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895418,0.001627495,0.001100066,0.0003018753,0.00005890874,0.00004749946,0.0005313287,0.000159038,0.006632026],"genre_scores_gemma":[0.9978382,0.0003781752,0.0005904678,0.0000666686,0.00006559339,0.00001231354,0.0001292757,0.0000386575,0.0008807415],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005619083,"threshold_uncertainty_score":0.0187977,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007156525535701411,"score_gpt":0.2012050708327751,"score_spread":0.1940485452970737,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}