{"id":"W2003723250","doi":"10.1016/j.gene.2006.04.012","title":"Role of p38 in stress activation of Sp1","year":2006,"lang":"en","type":"article","venue":"Gene","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Hospital for Sick Children; Agence Nationale pour la Gestion des Déchets Radioactifs; Heart and Stroke Foundation of Canada","keywords":"Filamin; Biology; Sp1 transcription factor; Transfection; Molecular biology; Phosphorylation; FLNA; p38 mitogen-activated protein kinases; Cell biology; Mutant; Protein kinase A; Promoter; Regulation of gene expression; Gene; Gene expression; Cell; Biochemistry; Cytoskeleton","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002754485,0.0006206541,0.0002624139,0.0002683316,0.0006942611,0.000344451,0.0003651449,0.0003853681,0.002692055],"category_scores_gemma":[0.0002425314,0.0002535448,0.000280824,0.0001015433,0.000405619,0.0006301206,0.0003657556,0.0006642643,0.0004410872],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004179203,"about_ca_system_score_gemma":0.0002050767,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003234007,"about_ca_topic_score_gemma":0.0003047129,"domain_scores_codex":[0.9998651,0.00002941683,0.000009657738,0.0000265886,0.00002933713,0.0000399211],"domain_scores_gemma":[0.9998567,0.00003661034,0.00002296678,0.00002094726,0.00002012475,0.00004259895],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004837106,0.00006101792,0.0005052236,0.00006127953,0.000004953293,0.0004411158,0.00007024968,0.0001416865,0.9946215,0.001237889,0.00007888644,0.002292331],"study_design_scores_gemma":[0.00003238933,0.00028688,0.01081372,0.000008147285,0.00000852124,0.0006996121,0.0001252592,0.00228539,0.9832703,0.001096108,0.001365458,0.000008285205],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9876679,0.00252915,0.006297382,0.0004922767,0.00007512383,0.00003462423,0.0001816685,0.00008347072,0.002638473],"genre_scores_gemma":[0.9951994,0.0005006682,0.001782497,0.00002619023,0.00002870553,0.00002880261,0.0001242993,0.00001031074,0.002298902],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002692055,"threshold_uncertainty_score":0.009005785,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003582334938933107,"score_gpt":0.206926058190695,"score_spread":0.2033437232517619,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}