{"id":"W2003773799","doi":"10.1182/blood-2010-01-263806","title":"Pathway discovery in mantle cell lymphoma by integrated analysis of high-resolution gene expression and copy number profiling","year":2010,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":136,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"National Cancer Institute","keywords":"Biology; CDKN2A; Mantle cell lymphoma; Gene expression profiling; Loss of heterozygosity; Gene dosage; Comparative genomic hybridization; Copy number analysis; Cancer research; Copy-number variation; Gene; Genetics; Locus (genetics); Gene expression; Lymphoma; Genome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004024047,0.0001835569,0.0002737913,0.0007269419,0.0001179023,0.0004256512,0.0002262099,0.0001669881,0.0003866639],"category_scores_gemma":[0.0005756865,0.0001365713,0.0002319634,0.0005629561,0.0001478724,0.0002048109,0.0002866362,0.0002345825,0.0001125438],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002463059,"about_ca_system_score_gemma":0.0002027591,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006525266,"about_ca_topic_score_gemma":0.001426742,"domain_scores_codex":[0.9997907,0.000045812,0.000009874168,0.00005342243,0.00007091402,0.00002919752],"domain_scores_gemma":[0.9998392,0.00005683989,0.00004717606,0.0000213858,0.00001902069,0.00001634787],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004968959,0.00007743423,0.06078907,0.0001206008,0.0001430989,0.000185089,0.00008745435,0.005766579,0.8733435,0.0004354206,0.0001185107,0.05843635],"study_design_scores_gemma":[0.00009191448,0.0006348126,0.3873622,0.00002203466,0.0003805278,0.001724409,0.0001638893,0.1276969,0.4761677,0.001967374,0.003735043,0.00005323038],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9778228,0.0007574563,0.02032417,0.00005854916,0.000002421776,0.00002813547,0.0005025419,0.0001721374,0.0003316378],"genre_scores_gemma":[0.9654263,0.0003402013,0.03282007,0.00003263365,0.000003919626,0.00004544915,0.0008915067,0.00002142936,0.0004184914],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007269419,"threshold_uncertainty_score":0.002128124,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005399649423686771,"score_gpt":0.2228407628115854,"score_spread":0.2174411133878986,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}