{"id":"W2003773799","doi":"10.1182/blood-2010-01-263806","title":"Pathway discovery in mantle cell lymphoma by integrated analysis of high-resolution gene expression and copy number profiling","year":2010,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":136,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"National Cancer Institute","keywords":"Biology; CDKN2A; Mantle cell lymphoma; Gene expression profiling; Loss of heterozygosity; Gene dosage; Comparative genomic hybridization; Copy number analysis; Cancer research; Copy-number variation; Gene; Genetics; Locus (genetics); Gene expression; Lymphoma; Genome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008251786,0.0001192486,0.0003232608,0.0001162069,0.00002629515,0.00001484587,0.00003514618,0.00009917117,0.00004355691],"category_scores_gemma":[0.00001953215,0.00008570246,0.00006893266,0.000310786,0.00003634795,0.00007764065,0.000030344,0.00005174061,0.000004330403],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003055433,"about_ca_system_score_gemma":0.00005849261,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000789159,"about_ca_topic_score_gemma":0.0001058228,"domain_scores_codex":[0.9992222,0.00002653232,0.0002260944,0.0002373116,0.0001461179,0.0001417906],"domain_scores_gemma":[0.9995539,0.00004532256,0.00008791943,0.0002108238,0.00003742604,0.00006465473],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005942042,0.002243929,0.5165747,0.00002124795,0.0001473115,0.00002653279,0.00005509975,0.000002079474,0.4801805,0.000034646,0.00005904182,0.0005954732],"study_design_scores_gemma":[0.005549141,0.00007223351,0.1869989,0.00004251155,0.0006974034,0.000007577506,0.00004768041,0.0001559353,0.8062938,0.00001135055,0.00005347673,0.0000699817],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988746,0.0003647551,0.00004625063,0.00003250739,0.00004718902,0.000195266,0.0001151969,0.00001494451,0.0003092604],"genre_scores_gemma":[0.9970095,0.0001123592,0.002296487,0.00002207426,0.00001983831,0.00003599157,0.0003564287,0.0000107169,0.0001366639],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3295757,"threshold_uncertainty_score":0.3494845,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005399649423686771,"score_gpt":0.2228407628115854,"score_spread":0.2174411133878986,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}