{"id":"W2003778270","doi":"10.1158/1538-7445.am2013-89","title":"Abstract 89: Parathyroid Hormone-related Protein (PTHrP) is critical for breast tumour metastasis and may constitute a novel target for therapeutic intervention.","year":2013,"lang":"en","type":"article","venue":"Cancer Research","topic":"Bone health and treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital","funders":"","keywords":"Cancer research; Western blot; Genetically modified mouse; Biology; Parathyroid hormone-related protein; Transgene; Metastasis; Matrigel; Cancer; Protein kinase B; Internal medicine; Angiogenesis; Endocrinology; Medicine; Signal transduction; Parathyroid hormone; Gene; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001200165,0.000320498,0.0002702863,0.0001664189,0.0001581224,0.0004849658,0.000255902,0.000461032,0.009428685],"category_scores_gemma":[0.0001513151,0.000151379,0.0002132758,0.0001684153,0.0002461955,0.0002736434,0.0002507064,0.0007551012,0.001803263],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003258997,"about_ca_system_score_gemma":0.0002391545,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004790873,"about_ca_topic_score_gemma":0.0004531365,"domain_scores_codex":[0.9998981,0.00001081937,0.000007138765,0.00002264743,0.00004120796,0.00002002991],"domain_scores_gemma":[0.9999278,0.00000793348,0.00002449173,0.000004764727,0.000008257525,0.00002690706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003485555,0.00005065169,0.0006456483,0.0002085346,0.0000112574,0.0002387899,0.00001110547,0.00004472871,0.9879025,0.0003696497,0.001149109,0.009019379],"study_design_scores_gemma":[0.0002594053,0.00173385,0.07028089,0.0001095323,0.0001165443,0.005850856,0.0001284143,0.001455064,0.86713,0.0009380037,0.0519803,0.00001718186],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9093812,0.0490109,0.008663797,0.004086981,0.0007699514,0.0001221628,0.005044031,0.0007636224,0.02215751],"genre_scores_gemma":[0.9680733,0.009496392,0.001977918,0.0003690776,0.0001880837,0.00006034878,0.002900257,0.00005643802,0.01687803],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009428685,"threshold_uncertainty_score":0.03154206,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1153314063810892,"score_gpt":0.4561021226257742,"score_spread":0.340770716244685,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}