{"id":"W2003846076","doi":"10.1021/bi011572e","title":"Role of Helix 3 in Pore Formation by the <i>Bacillus thuringiensis</i> Insecticidal Toxin Cry1Aa","year":2002,"lang":"en","type":"article","venue":"Biochemistry","topic":"Insect Resistance and Genetics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Biotechnology Research Institute","funders":"","keywords":"Bacillus thuringiensis; Manduca sexta; Chemistry; Biochemistry; Brush border; Midgut; Mutant; Biophysics; Amino acid; Helix (gastropod); Vesicle; Biology; Membrane; Botany; Larva","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009750713,0.00013608,0.0001106573,0.00001783145,0.00004997656,0.00001351126,0.00021431,0.0001768239,0.00002959326],"category_scores_gemma":[0.00005119706,0.0001144791,0.00007118766,0.0001121276,0.00008443712,0.000003793911,0.00006666787,0.00009767237,0.000004349551],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002115342,"about_ca_system_score_gemma":0.00002163766,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001546771,"about_ca_topic_score_gemma":0.00003226153,"domain_scores_codex":[0.999158,0.0000228538,0.0002447113,0.000205876,0.0001451626,0.0002233443],"domain_scores_gemma":[0.9994226,0.000008358944,0.00009981989,0.0003705627,0.00006026439,0.00003843477],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002858186,0.00006425325,0.0004498089,0.0000351548,0.00001046736,0.000001162869,0.0001131484,0.00001616229,0.9909936,0.000004253353,0.006638251,0.00164518],"study_design_scores_gemma":[0.0003236672,0.00006127846,0.0002759084,0.00001548694,0.000007007415,0.00002316989,0.0002540494,0.0001188353,0.9855182,0.0000283406,0.01323753,0.0001364845],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885046,0.005910368,0.00003340449,0.0001176236,0.00003335399,0.00009752104,0.00003823887,0.000006862117,0.00525797],"genre_scores_gemma":[0.9981608,0.0003550272,0.00007523665,0.0001979245,0.0001095513,0.00001522257,0.0001270564,0.00001309506,0.0009461288],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0096561,"threshold_uncertainty_score":0.4668322,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005125779616566532,"score_gpt":0.1913341170748325,"score_spread":0.186208337458266,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}