{"id":"W2003846076","doi":"10.1021/bi011572e","title":"Role of Helix 3 in Pore Formation by the <i>Bacillus thuringiensis</i> Insecticidal Toxin Cry1Aa","year":2002,"lang":"en","type":"article","venue":"Biochemistry","topic":"Insect Resistance and Genetics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Biotechnology Research Institute","funders":"","keywords":"Bacillus thuringiensis; Manduca sexta; Chemistry; Biochemistry; Brush border; Midgut; Mutant; Biophysics; Amino acid; Helix (gastropod); Vesicle; Biology; Membrane; Botany; Larva","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002087334,0.0003102986,0.0001742027,0.00008037798,0.0002475114,0.0003364835,0.0001629209,0.0005509216,0.0005969145],"category_scores_gemma":[0.0001868379,0.0001151079,0.000414157,0.00006098965,0.0002931111,0.0003033824,0.0002163259,0.0004537278,0.0004657637],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002887485,"about_ca_system_score_gemma":0.0002353733,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005025824,"about_ca_topic_score_gemma":0.000498399,"domain_scores_codex":[0.9998745,0.00003369143,0.00001157809,0.00002031926,0.00003125424,0.00002868397],"domain_scores_gemma":[0.9997788,0.00003873837,0.00009283268,0.00001311227,0.00002203666,0.00005447524],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003062717,0.00002673849,0.001018366,0.00002769198,0.000005312648,0.0002334321,0.00002615862,0.0002360466,0.997144,0.0001382015,0.00002964961,0.0008079743],"study_design_scores_gemma":[0.00007015828,0.0004198065,0.0178011,0.00003146266,0.0000297002,0.001243276,0.0000922785,0.003946214,0.9747911,0.0002904141,0.001262441,0.00002197975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975951,0.0002629541,0.001345695,0.00006352703,0.00001122411,0.000009446385,0.00005003289,0.00003756758,0.0006244317],"genre_scores_gemma":[0.9986665,0.0001247306,0.0007634567,0.00004653132,0.000003016266,0.00000411469,0.0001009391,0.00000738396,0.000283379],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005969145,"threshold_uncertainty_score":0.002095044,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005125779616566532,"score_gpt":0.1913341170748325,"score_spread":0.186208337458266,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}