{"id":"W2004027078","doi":"10.1111/jnc.12068","title":"Omega‐3 fatty acid eicospentaenoic acid attenuates <scp>MPP</scp><sup>+</sup>‐induced neurodegeneration in fully differentiated human <scp>SH</scp>‐<scp>SY</scp>5Y and primary mesencephalic cells","year":2012,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; University of Prince Edward Island; University of Alberta","funders":"Amarin Corporation","keywords":"Neuroprotection; Eicosapentaenoic acid; Arachidonic acid; SH-SY5Y; Neurodegeneration; Reactive oxygen species; Biochemistry; Chemistry; Nitric oxide; Cell biology; Pharmacology; Biology; Fatty acid; Polyunsaturated fatty acid; Cell culture; Enzyme; Internal medicine; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001296052,0.0004459904,0.0005132498,0.0002458167,0.0001669053,0.0002677017,0.0001867446,0.0003330977,0.0008579223],"category_scores_gemma":[0.0001146519,0.0001473782,0.0004007556,0.0002036618,0.0002395251,0.0003452516,0.0002466285,0.0008194177,0.0002840231],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002355579,"about_ca_system_score_gemma":0.0004305575,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001991052,"about_ca_topic_score_gemma":0.003359133,"domain_scores_codex":[0.9998913,0.00001373703,0.00002334649,0.00001834033,0.00002778213,0.00002555239],"domain_scores_gemma":[0.999903,0.00001006936,0.00002242317,0.0000134568,0.00002259322,0.00002838705],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006598828,0.00006845113,0.0001447361,0.00007053388,0.00001352807,0.00009627002,0.00002285185,0.00004385646,0.9975458,0.00004042829,0.00005453727,0.001239049],"study_design_scores_gemma":[0.00005715151,0.001425994,0.01106642,0.00002343586,0.00006499627,0.0002641359,0.0001006046,0.0005764872,0.9839383,0.00006804642,0.002407376,0.000007175611],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943532,0.002568095,0.000991281,0.0001189549,0.00006067736,0.00002713504,0.0006926179,0.00004434638,0.001143581],"genre_scores_gemma":[0.9889084,0.003395599,0.001860503,0.0001333357,0.00002822229,0.00008973764,0.001715458,0.00002460493,0.003844202],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001991052,"threshold_uncertainty_score":0.003958881,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01965418271366828,"score_gpt":0.2535636659612636,"score_spread":0.2339094832475953,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}