{"id":"W2004080374","doi":"10.1002/jbm.a.32096","title":"Effect of alginate on innate immune activation of macrophages","year":2008,"lang":"en","type":"article","venue":"Journal of Biomedical Materials Research Part A","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":165,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Innate immune system; Proinflammatory cytokine; Lipopolysaccharide; Macrophage; Inflammation; Immune system; Stimulation; Cell biology; Tumor necrosis factor alpha; Immunology; Materials science; Biology; Biochemistry; Neuroscience; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.005576445,0.0001110797,0.0005653091,0.0006297887,0.0001077515,0.000006789557,0.0002754545,0.0002277187,0.001011605],"category_scores_gemma":[0.001767257,0.00007299038,0.0001116665,0.0002955166,0.0007784669,0.000130025,0.0000805153,0.0003516999,0.00009351352],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004202399,"about_ca_system_score_gemma":0.0001532412,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002950828,"about_ca_topic_score_gemma":3.665288e-8,"domain_scores_codex":[0.9960926,0.002253274,0.0009518106,0.00009820973,0.0003129183,0.0002911434],"domain_scores_gemma":[0.9978309,0.0009551776,0.0005769595,0.0001838676,0.0004192508,0.00003380346],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007091169,0.0001739551,0.00002469473,0.0001684428,0.0001552514,0.0000312608,0.0002019017,6.946365e-7,0.98457,0.00004972547,0.0027878,0.004745145],"study_design_scores_gemma":[0.001946435,0.006045909,0.002295186,0.0004172933,0.00001214619,0.0001311128,0.00002413661,5.61289e-7,0.9807268,0.00004074448,0.008307245,0.00005241191],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981502,0.0005246773,0.0000245608,0.0004223741,0.0005759824,0.000189879,0.00001218969,0.000005115842,0.00009498217],"genre_scores_gemma":[0.9989336,0.0005997158,0.0000143768,0.000006934608,0.00008971752,0.000006498673,0.00002403552,0.00001008993,0.0003150968],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005871954,"threshold_uncertainty_score":0.9999016,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02887547502372464,"score_gpt":0.3471030407203116,"score_spread":0.3182275656965869,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}