{"id":"W2004131059","doi":"10.1016/j.neurobiolaging.2004.09.003","title":"Apolipoprotein E, cholesterol transport and synthesis in sporadic Alzheimer's disease","year":2004,"lang":"en","type":"review","venue":"Neurobiology of Aging","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":159,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Alzheimer Society","keywords":"Apolipoprotein E; Probucol; Internal medicine; Endocrinology; Cholesterol; Alzheimer's disease; Apolipoprotein B; Medicine; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001504843,0.0004633271,0.00188883,0.0005292686,0.00004303222,0.000005437358,0.0001553922,0.0002201198,0.00003639613],"category_scores_gemma":[0.00003024649,0.0003650237,0.0003757432,0.0002511781,0.0003674545,0.00005708662,0.00005013848,0.0004635853,0.00002046197],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000622762,"about_ca_system_score_gemma":0.000698954,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001665195,"about_ca_topic_score_gemma":0.000009777104,"domain_scores_codex":[0.9978967,0.0001850013,0.0006044628,0.0006602079,0.0001642013,0.0004894225],"domain_scores_gemma":[0.9986861,0.0001465603,0.0002229191,0.0004566987,0.00002853701,0.0004591746],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0004673509,0.002593711,0.06478948,0.07459842,0.01688267,0.005667532,0.0001111766,0.000003014155,0.000001407733,0.00008684031,0.00002127841,0.8347771],"study_design_scores_gemma":[0.01720834,0.002491427,0.4366454,0.350437,0.1096439,0.002009849,0.00006286591,0.000008290397,0.0002448476,0.0005023121,0.07707839,0.003667337],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.009848638,0.9882519,4.234319e-7,0.0001162436,0.00004488272,0.001463618,0.0001633913,0.0000362965,0.0000746631],"genre_scores_gemma":[0.08233172,0.9170642,0.00004232895,0.00004185393,0.00005035522,0.000207087,0.0001917579,0.00006501008,0.000005701612],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8311098,"threshold_uncertainty_score":0.9998802,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04896671988787202,"score_gpt":0.3396386556900797,"score_spread":0.2906719358022077,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}