{"id":"W2004143596","doi":"10.1016/j.vaccine.2004.02.011","title":"An adenoviral type 5 vector carrying a type 35 fiber as a vaccine vehicle: DC targeting, cross neutralization, and immunogenicity","year":2004,"lang":"en","type":"article","venue":"Vaccine","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"Leids Universitair Medisch Centrum","keywords":"Immunogenicity; Viral vector; Tropism; Virology; Biology; Ex vivo; Transduction (biophysics); Immunity; Adenoviridae; Immune system; Vector (molecular biology); Vaccination; In vivo; Immunology; Genetic enhancement; Recombinant DNA; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003759796,0.0005383627,0.00026502,0.0003913435,0.0002122678,0.000343176,0.000274051,0.0003646386,0.0008370792],"category_scores_gemma":[0.0002025365,0.0001992099,0.0002249402,0.0001734184,0.0003188015,0.000445183,0.0002014604,0.0006124823,0.0002090005],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004927503,"about_ca_system_score_gemma":0.0004709806,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001181939,"about_ca_topic_score_gemma":0.001085026,"domain_scores_codex":[0.9998386,0.00002310296,0.00001448258,0.00002845129,0.00004948138,0.00004588034],"domain_scores_gemma":[0.9999061,0.00001885694,0.00002269626,0.00001118658,0.00001653546,0.00002467343],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003268099,0.0000680621,0.0002087552,0.00003924216,0.000008217457,0.00003952732,0.00002130985,0.0002492359,0.9937662,0.0008938842,0.00007584423,0.004302964],"study_design_scores_gemma":[0.00001957564,0.0004237733,0.0005074685,0.000003866151,0.00002312984,0.0002430379,0.000009033208,0.001156367,0.995321,0.0001666512,0.002122365,0.000003815109],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.944728,0.006268491,0.0441,0.0003275808,0.00009800436,0.0001831207,0.0004191764,0.0002471768,0.003628552],"genre_scores_gemma":[0.9857553,0.001280497,0.008431871,0.00005531895,0.00001801309,0.00003741679,0.0005440828,0.00003162813,0.003845884],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001181939,"threshold_uncertainty_score":0.003575206,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01131056061307245,"score_gpt":0.3096905114532381,"score_spread":0.2983799508401656,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}