{"id":"W2004153631","doi":"10.1021/bi060283t","title":"Catalysis of Covalent Lp(a) Assembly:  Evidence for an Extracellular Enzyme Activity that Enhances Disulfide Bond Formation","year":2006,"lang":"en","type":"article","venue":"Biochemistry","topic":"Biotin and Related Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Covalent bond; Disulfide bond; Chemistry; Extracellular; Enzyme; Biochemistry; Biophysics; Stereochemistry; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002061996,0.0001826089,0.0001941452,0.00002115944,0.000113051,0.00002038519,0.0001832192,0.0002737878,0.000003431318],"category_scores_gemma":[0.00007634872,0.0001639742,0.0001623228,0.00007082182,0.0001204454,0.00001663313,0.00006845884,0.00007054095,0.000001295367],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002386571,"about_ca_system_score_gemma":0.00004949824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005769942,"about_ca_topic_score_gemma":0.00003964777,"domain_scores_codex":[0.9990306,0.00002215003,0.0002241238,0.0003582262,0.0001424128,0.0002224666],"domain_scores_gemma":[0.9992136,0.00003177917,0.0002256543,0.0003686562,0.0001084373,0.00005182741],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001140473,0.0001349455,0.0004192946,0.0002227857,0.00005686637,5.412642e-7,0.00002005871,0.00001700839,0.9957418,0.000008383983,0.002584264,0.0006800359],"study_design_scores_gemma":[0.0002852017,0.000131796,0.0005054509,0.0000655088,0.00007714002,0.00000645827,0.0001084129,0.0001878851,0.9971013,0.00002607981,0.001299543,0.0002052193],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9807429,0.01093034,0.00756659,0.0001043921,0.00007776208,0.0001867323,0.00004846024,0.00001604084,0.000326758],"genre_scores_gemma":[0.9970784,0.0006242687,0.0007160257,0.00001236509,0.0002067054,0.00003679773,0.0002881686,0.00001481271,0.001022485],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01633545,"threshold_uncertainty_score":0.6686675,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03375078076459329,"score_gpt":0.2975663015880433,"score_spread":0.2638155208234499,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}