{"id":"W2004245714","doi":"10.1097/hjh.0b013e328330a963","title":"Aldosterone induces arterial stiffness in absence of oxidative stress and endothelial dysfunction","year":2009,"lang":"en","type":"article","venue":"Journal of Hypertension","topic":"Hormonal Regulation and Hypertension","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Endocrinology; Aldosterone; Internal medicine; Oxidative stress; Mineralocorticoid; Myograph; Nicotinamide adenine dinucleotide phosphate; Endothelial dysfunction; Medicine; Mesenteric arteries; Reactive oxygen species; Oxidase test; Eplerenone; Endothelium; Mineralocorticoid receptor; Chemistry; Biochemistry; Artery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001855273,0.00009797616,0.000414848,0.0002416393,0.00002525865,0.000008835826,0.00003511118,0.00008289998,0.00001883129],"category_scores_gemma":[0.0001478217,0.00006813127,0.0000517019,0.0001174042,0.00004731736,0.0001865154,0.00001158425,0.0001686233,0.000001264488],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002883899,"about_ca_system_score_gemma":0.00006456563,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001347112,"about_ca_topic_score_gemma":0.00000392863,"domain_scores_codex":[0.998973,0.00004269942,0.0004400313,0.0001044942,0.000337625,0.000102131],"domain_scores_gemma":[0.9991602,0.00005201701,0.0002715844,0.00008214088,0.000343197,0.00009080109],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002207995,0.0002402936,0.0009015523,0.00001512687,0.00001543167,0.0002193001,0.0001862557,0.00001221048,0.9448153,0.00003479065,0.00008258045,0.05126919],"study_design_scores_gemma":[0.006141843,0.001326366,0.9244355,0.0007642742,0.00007284828,0.001598088,0.0004176706,0.0004063022,0.0643202,0.0001936727,0.0002300892,0.00009317061],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976369,0.000350055,0.00005491261,0.001576254,0.0002169854,0.0001005831,0.000002355701,0.000004058875,0.00005793106],"genre_scores_gemma":[0.9987192,0.0002080358,0.0005893054,0.0002617344,0.0001879821,2.256799e-7,0.000002671254,0.000005945561,0.00002491454],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9235339,"threshold_uncertainty_score":0.2778313,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03248370935452743,"score_gpt":0.261420575207534,"score_spread":0.2289368658530065,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}