{"id":"W2004262894","doi":"10.1159/000338153","title":"Transthyretin Aggregates Induce Production of Reactive Nitrogen Species","year":2012,"lang":"en","type":"article","venue":"Neurodegenerative Diseases","topic":"Amyloidosis: Diagnosis, Treatment, Outcomes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Chemistry; Reactive nitrogen species; Cell culture; Neurodegeneration; Nitrite; Molecular biology; Biochemistry; Internal medicine; Reactive oxygen species; Biology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002242403,0.0004947039,0.0003031971,0.0002421049,0.0001362655,0.0002307524,0.0001826618,0.0005463121,0.0007672972],"category_scores_gemma":[0.000234407,0.0001365023,0.0004497191,0.0001332286,0.0001881297,0.0001981774,0.0002548093,0.0004618374,0.0003013142],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002018908,"about_ca_system_score_gemma":0.0001187431,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006290792,"about_ca_topic_score_gemma":0.0006710737,"domain_scores_codex":[0.99965,0.00008111586,0.0000373751,0.00006581385,0.0001191539,0.0000464206],"domain_scores_gemma":[0.9997655,0.00003695479,0.00008140274,0.00003365994,0.00005460329,0.00002796579],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009504119,0.00002125651,0.0001998892,0.00002092915,0.000005847508,0.00009199285,0.00001789984,0.00001543537,0.9991924,0.000008274202,0.0000126013,0.0003184048],"study_design_scores_gemma":[0.00001473097,0.000798658,0.00780735,0.00001011901,0.00001949638,0.0005607203,0.00006375,0.0004483989,0.9893268,0.00004144586,0.0009036604,0.000004897921],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951097,0.002064586,0.001367149,0.00005724044,0.00003416092,0.00002845419,0.00008841947,0.00005036808,0.00119995],"genre_scores_gemma":[0.9960247,0.0007652682,0.001438519,0.00005244357,0.0000175125,0.00003017676,0.0002174713,0.000008669193,0.001445192],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007672972,"threshold_uncertainty_score":0.002566814,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0167672173117462,"score_gpt":0.2581860477524994,"score_spread":0.2414188304407532,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}