{"id":"W2004306343","doi":"10.1159/000229787","title":"Phase IV Study of Bevacizumab in Combination with Infusional Fluorouracil, Leucovorin and Irinotecan (FOLFIRI) in First-Line Metastatic Colorectal Cancer","year":2009,"lang":"en","type":"article","venue":"Oncology","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":118,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sudbury Regional Hospital; University of Toronto","funders":"","keywords":"Bevacizumab; FOLFIRI; Medicine; Irinotecan; Colorectal cancer; Fluorouracil; Internal medicine; Neutropenia; Phases of clinical research; Bolus (digestion); Adverse effect; Oncology; Gastroenterology; Surgery; Chemotherapy; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001276729,0.001509842,0.002846023,0.0005151557,0.0004036029,0.001242458,0.001460008,0.001515068,0.002443089],"category_scores_gemma":[0.001338898,0.0006936947,0.0009462133,0.0005823375,0.0008815419,0.0005903344,0.0003321771,0.003001899,0.0006608202],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001674552,"about_ca_system_score_gemma":0.002158402,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001947306,"about_ca_topic_score_gemma":0.004021842,"domain_scores_codex":[0.9994972,0.00023413,0.0000273217,0.00008861667,0.00005525793,0.00009746988],"domain_scores_gemma":[0.9990078,0.0001645852,0.000230517,0.00006265238,0.00007775264,0.0004567489],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5997078,0.1733924,0.01137172,0.001452127,0.003102651,0.0005526734,0.0004119748,0.003919574,0.07847476,0.0001892349,0.005445239,0.1219799],"study_design_scores_gemma":[0.5997092,0.3748141,0.01160632,0.00005282359,0.0007315818,0.0004853841,0.00004484953,0.001892697,0.007609115,0.00009283781,0.002934163,0.00002701255],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925937,0.002815804,0.000660309,0.0002983763,0.0001245739,0.001962742,0.0004807265,0.0001097534,0.0009538894],"genre_scores_gemma":[0.988951,0.001967391,0.002526537,0.0005260286,0.0002077086,0.002061028,0.002397269,0.00003496107,0.001328004],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002846023,"threshold_uncertainty_score":0.01214975,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03083168194768317,"score_gpt":0.3612338398705704,"score_spread":0.3304021579228872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}