{"id":"W2004321823","doi":"10.1002/ana.22446","title":"Gene therapy for pain: Results of a phase I clinical trial","year":2011,"lang":"en","type":"article","venue":"Annals of Neurology","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":167,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Research Resources; National Institute of Neurological Disorders and Stroke; National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Medicine; Cancer pain; Adverse effect; Placebo; Ketamine; McGill Pain Questionnaire; Radicular pain; Clinical trial; Opioid; Anesthesia; Internal medicine; Cancer; Surgery; Visual analogue scale; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002565356,0.001214247,0.001689037,0.0003656732,0.00036025,0.0009813762,0.0008410311,0.002001796,0.004874228],"category_scores_gemma":[0.001482144,0.0002740201,0.001230328,0.0005128192,0.0008746673,0.0008599747,0.0002031818,0.001892737,0.001011454],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006071036,"about_ca_system_score_gemma":0.001194634,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004975138,"about_ca_topic_score_gemma":0.0007082731,"domain_scores_codex":[0.9993844,0.0002662949,0.00003972494,0.00009663279,0.0001045884,0.0001084069],"domain_scores_gemma":[0.9991875,0.0002393586,0.0001860119,0.00006712066,0.0001035959,0.0002162848],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5550885,0.06068185,0.004433498,0.005679163,0.002752689,0.0007502682,0.000493131,0.002519236,0.1035637,0.0007938431,0.01446934,0.2487748],"study_design_scores_gemma":[0.5934407,0.3849964,0.006733319,0.0002598259,0.0006641527,0.0003603199,0.00004680169,0.0009372354,0.006031631,0.0002755288,0.006224019,0.00003005621],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9425927,0.02809381,0.004647377,0.003534346,0.0007528848,0.00985004,0.003583531,0.0004876998,0.006457545],"genre_scores_gemma":[0.9498024,0.02073713,0.005512541,0.003888244,0.0009687354,0.01006807,0.004041736,0.00009905688,0.004882039],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004874228,"threshold_uncertainty_score":0.01630592,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4590816886586612,"score_gpt":0.4848119857603723,"score_spread":0.0257302971017111,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}